Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 1/20 | 0.62 |
| ▸ | HTR2C | P28335 | 6/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21471548 | 0.84 | HDAC4 (0.74) | QDPRHDAC4HDAC2HDAC8KMO | |
| SCHEMBL21471547 | 0.83 | HDAC4 (0.72) | QDPRHDAC4HDAC2HDAC8MAPT | |
| SCHEMBL23258680 | 0.80 | HDAC4 (0.54) | QDPRHDAC4HDAC2HDAC8KMO | |
| SCHEMBL366769 | 0.79 | HTR2C (0.62) | QDPRHTR2CSLC18A3SIGMAR1 | |
| SCHEMBL29664365 | 0.79 | HTR2C (0.62) | QDPRHTR2CSLC18A3SIGMAR1 | |
| SCHEMBL23250752 | 0.79 | HDAC4 (0.53) | QDPRHTR2CHDAC4HDAC2HDAC8 | |
| SCHEMBL8385390 | 0.77 | QDPR (1.00) | QDPRHTR2CSLC18A3SIGMAR1 | |
| SCHEMBL23250721 | 0.76 | HDAC4 (0.49) | QDPRHDAC4HDAC2HDAC8KMO | |
| SCHEMBL17274029 | 0.75 | HTR2C (0.62) | QDPRHTR2CSLC18A3SIGMAR1HTR6 | |
| SCHEMBL23250778 | 0.74 | HDAC4 (0.47) | QDPRHDAC4HDAC2HDAC8KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073131-A2 | METHOD OF TREATING NEURODEGENERATIVE DISEASES | THE BOARD OF TRUSTEES OF THE UNIVESITY OF ILLINOIS (US) | 2024-04-04 | — | — | WO | disclosed |
| WO-2021076938-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | Ambys Medicines, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |