Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.47 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23263868 | 0.92 | L3MBTL1 (0.46) | L3MBTL1MAPTLMNAMAPK1TDP1 | |
| SCHEMBL23258867 | 0.87 | MAPT (0.59) | L3MBTL1MAPTMAPK1TDP1LTA4H | |
| SCHEMBL23258790 | 0.82 | APP (0.55) | L3MBTL1MAPTMAPK1TDP1LTA4H | |
| SCHEMBL11147828 | 0.82 | MAOB (0.59) | L3MBTL1MAPTMAPK1TDP1LTA4H | |
| SCHEMBL23258431 | 0.82 | RAB9A (0.49) | L3MBTL1MAPTMAPK1TDP1LTA4H | |
| SCHEMBL23259192 | 0.82 | PTGER1 (0.50) | L3MBTL1MAPTLMNAMAPK1TDP1 | |
| SCHEMBL23258799 | 0.82 | MAPT (0.55) | L3MBTL1MAPTLMNAMAPK1TDP1 | |
| SCHEMBL23258866 | 0.79 | MAPK14 (0.51) | L3MBTL1MAPTLMNAMAPK1TDP1 | |
| SCHEMBL23263939 | 0.78 | L3MBTL1 (0.48) | L3MBTL1MAPTLMNAMAPK1TDP1 | |
| SCHEMBL23258545 | 0.78 | PPIA (0.49) | L3MBTL1MAPTLMNAMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076938-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | Ambys Medicines, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |