Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | CCR5 | P51681 | 1/20 | 0.47 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.46 |
| ▸ | PPIA | P62937 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23258867 | 0.83 | MAPT (0.59) | PTGER1MAPK14MAPTL3MBTL1MAPK1 | |
| SCHEMBL23258790 | 0.82 | APP (0.55) | MAPK14SMN1; SMN2MAPTL3MBTL1MAPK1 | |
| SCHEMBL11147828 | 0.82 | MAOB (0.59) | MAPK14SMN1; SMN2MAPTL3MBTL1MAPK1 | |
| SCHEMBL23258693 | 0.82 | L3MBTL1 (0.51) | PTGER1MAPK14KMT2AALDH1A1LMNA | |
| SCHEMBL23258431 | 0.82 | RAB9A (0.49) | MAPK14SLC6A4CCR5ALDH1A1HTT | |
| SCHEMBL23258799 | 0.82 | MAPT (0.55) | PTGER1MAPK14ALDH1A1LMNAHTT | |
| SCHEMBL23259194 | 0.76 | PTGER1 (0.51) | PTGER1MAPK14SLC6A4JAK2ZAP70 | |
| SCHEMBL23259193 | 0.76 | MRGPRX4 (0.58) | PTGER1SLC6A4JAK2ZAP70MAPT | |
| SCHEMBL23258555 | 0.76 | MAOB (0.49) | MEN1KMT2AATMKDM4ESMN1; SMN2 | |
| SCHEMBL23263868 | 0.76 | L3MBTL1 (0.46) | MAPK14MEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076938-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | Ambys Medicines, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |