Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 14/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31286395 | 0.85 | PIK3R1 (0.34) | PIK3R1PIK3CAAR | |
| SCHEMBL29725973 | 0.75 | RET (0.41) | PIK3R1PIK3CAAR | |
| SCHEMBL6858269 | 0.74 | KIF11 (0.34) | — | |
| SCHEMBL10671983 | 0.73 | PIK3R1 (0.41) | PIK3R1PIK3CAAR | |
| SCHEMBL21459566 | 0.72 | HTR1A (0.42) | — | |
| SCHEMBL30972827 | 0.72 | CACNA1H (0.38) | PIK3R1PIK3CAAR | |
| Bromide SCHEMBL29864117 | 0.71 | HTR1A (0.41) | — | |
| SCHEMBL31089241 | 0.70 | HTR1A (0.45) | AR | |
| SCHEMBL27295875 | 0.70 | SLC6A4 (0.45) | AR | |
| SCHEMBL31089045 | 0.69 | HTR2A (0.46) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076902-A1 | INHIBITING HUMAN INTEGRIN α 4 β 7 | MORPHIC THERAPEUTIC, INC. (US) | 2021-04-22 | — | — | WO | disclosed |