Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.45 |
| ▸ | MPO | P05164 | 2/20 | 0.45 |
| ▸ | HTR1D | P28221 | 3/20 | 0.44 |
| ▸ | HTR1B | P28222 | 2/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 7/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31089045 | 0.87 | HTR2A (0.46) | HTR1AMPOHTR1DHTR1BHTR2A | |
| SCHEMBL21459566 | 0.85 | HTR1A (0.42) | HTR1AMPOHTR1DHTR1BHTR6 | |
| Bromide SCHEMBL29864117 | 0.84 | HTR1A (0.41) | HTR1AMPOHTR1DHTR1BHTR6 | |
| SCHEMBL27295875 | 0.79 | SLC6A4 (0.45) | HTR1AMPOHTR1DHTR1BHTR2A | |
| SCHEMBL30972827 | 0.76 | CACNA1H (0.38) | HTR2AAR | |
| SCHEMBL29725973 | 0.75 | RET (0.41) | HTR2AAR | |
| SCHEMBL27297250 | 0.70 | PIK3R1 (0.34) | MPO | |
| SCHEMBL23259495 | 0.70 | PIK3R1 (0.37) | AR | |
| SCHEMBL31089289 | 0.70 | MPO (0.46) | HTR1AMPOHTR1DHTR1BHTR2A | |
| SCHEMBL23249136 | 0.70 | HTR2A (0.43) | HTR1AMPOHTR1DHTR1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175907-A1 | MACROCYCLIC ALPHA4BETA7 INTEGRIN INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2024-08-29 | — | — | WO | disclosed |