Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.31 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL71090 | 0.81 | SMARCA2 (0.41) | GRM5KDM4EALDH1A1SMARCA2SMARCA4 | |
| SCHEMBL27671792 | 0.74 | GRM5 (0.40) | GRM5KDM4EALDH1A1SMARCA2SMARCA4 | |
| SCHEMBL1400929 | 0.68 | ALDH1A1 (0.46) | GRM5KDM4EALDH1A1SMARCA2SMARCA4 | |
| SCHEMBL1459501 | 0.68 | CCNC (0.44) | GRM5KDM4EALDH1A1SMARCA2SMARCA4 | |
| SCHEMBL3550705 | 0.67 | RORC (0.33) | — | |
| SCHEMBL27690798 | 0.65 | CCNC (0.35) | GRM5KDM4EALDH1A1SMARCA2SMARCA4 | |
| SCHEMBL25216054 | 0.65 | AR (0.45) | GRM5KDM4EALDH1A1CNR2 | |
| SCHEMBL15880966 | 0.63 | NPSR1 (0.42) | KDM4EALDH1A1SMARCA2SMARCA4 | |
| SCHEMBL29799450 | 0.62 | ATR (0.40) | GRM5KDM4EALDH1A1SMARCA2SMARCA4 | |
| SCHEMBL7503086 | 0.62 | ATR (0.40) | GRM5KDM4EALDH1A1SMARCA2SMARCA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273759-B2 | Fungicide heterocyclyl-pyrimidinyl-amino derivatives | BAYER CROPSCIENCE AG (DE) | 2012-09-25 | — | — | US | disclosed |
| US-20110218188-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-09-08 | — | — | US | disclosed |
| EP-2356107-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-17 | — | — | EP | disclosed |
| US-20100204229-A1 | FUNGICIDE HETEROCYCLYL-PYRIMIDINYL-AMINO DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110218188-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | CYP1A1, CYP1A2, PNPO | GRM5 2422/4885KDM4E 315/4885ALDH1A1 346/4885 |
| US-20100204229-A1 | FUNGICIDE HETEROCYCLYL-PYRIMIDINYL-AMINO DERIVATIVES | PAH, CYP4X1, PRXL2A | GRM5 2376/4885KDM4E 762/4885ALDH1A1 1331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.