Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 14/20 | 0.60 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.32 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21587610 | 1.00 | BRD4 (0.60) | BRD4PIK3CDPOLBMMEKAT2B | |
| SCHEMBL8146692 | 1.00 | BRD4 (0.60) | BRD4PIK3CDPOLBMMEKAT2B | |
| SCHEMBL2030149 | 0.82 | BRD4 (0.58) | BRD4 | |
| SCHEMBL19296766 | 0.81 | BRD4 (0.43) | BRD4PIK3CDMMEKAT2BKAT2A | |
| SCHEMBL19570437 | 0.81 | BRD4 (0.43) | BRD4PIK3CDPOLBMME | |
| SCHEMBL23809745 | 0.78 | POLB (0.41) | BRD4PIK3CDPOLBMME | |
| SCHEMBL15600032 | 0.78 | BRD4 (0.40) | BRD4POLBMME | |
| SCHEMBL23809763 | 0.78 | POLB (0.41) | BRD4PIK3CDPOLBMME | |
| SCHEMBL9259167 | 0.78 | MAPT (0.50) | BRD4POLBMME | |
| SCHEMBL19592340 | 0.77 | POLB (0.40) | BRD4PIK3CDPOLBMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210114972-A1 | METHOD FOR PREPARING PREGABALIN | ZHEJIANG HUAHAI PHARMACEUTICAL CO., LTD. (CN) | 2021-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210114972-A1 | METHOD FOR PREPARING PREGABALIN | GABRD, GABRB2, GABRP | BRD4 3788/4885PIK3CD 2589/4885POLB 693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.