Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 8/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.31 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23265386 | 0.91 | ALDH1A1 (0.46) | ALDH1A1KDM4EPIK3CDMEN1KMT2A | |
| SCHEMBL23265497 | 0.91 | ALDH1A1 (0.50) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23265370 | 0.89 | ALDH1A1 (0.36) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23265368 | 0.88 | ABCB1 (0.35) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23265380 | 0.88 | ALDH1A1 (0.37) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23265364 | 0.87 | ALDH1A1 (0.40) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4510196 | 0.87 | ALDH1A1 (0.40) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4517075 | 0.85 | LMNA (0.46) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29919550 | 0.84 | NR2F2 (0.40) | ALDH1A1PIK3CDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4400281 | 0.84 | NR2F2 (0.40) | ALDH1A1PIK3CDMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021074309-A1 | 1-(3-QUINOLYL)-3,4-DIHYDROISOQUINOLINE DERIVATIVES AS FUNGICIDES FOR COMBATING SPECIFIC PHYTOPATHOGENS | SYNGENTA CROP PROTECTION AG (CH) | 2021-04-22 | — | — | WO | disclosed |