SCHEMBL4400281

SCHEMBL4400281

CC1(C)Cc2c(Cl)cccc2C(c2cnc3ccccc3c2)=N1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR2F2 P24468 1/20 0.40
BRD4 O60885 2/20 0.39
CREBBP Q92793 2/20 0.39
BIRC5 O15392 1/20 0.39
PDGFRB P09619 3/20 0.38
PDGFRA P16234 3/20 0.38
MAP4K4 O95819 1/20 0.38
CSNK1G2 P78368 1/20 0.38
CLK4 Q9HAZ1 1/20 0.38
MKNK2 Q9HBH9 1/20 0.38
MAP4K5 Q9Y4K4 1/20 0.38
PARP10 Q53GL7 1/20 0.37
PARP11 Q9NR21 1/20 0.37
CYP2A6 P11509 1/20 0.36
AKR1C3 P42330 1/20 0.36
AKR1C2 P52895 1/20 0.36
NISCH Q9Y2I1 1/20 0.36
ALDH1A1 P00352 2/20 0.36
TDP2 O95551 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29919550 1.00 NR2F2 (0.40) NR2F2BRD4CREBBPBIRC5PDGFRB
SCHEMBL4530992 0.87 NR2F2 (0.39) NR2F2BRD4CREBBPBIRC5PDGFRB
SCHEMBL4527597 0.87 ALDH1A1 (0.49) NR2F2BRD4CREBBPBIRC5PDGFRB
SCHEMBL4529985 0.87 BIRC5 (0.42) NR2F2BRD4CREBBPBIRC5PDGFRB
SCHEMBL4523639 0.86 NR2F2 (0.41) NR2F2BRD4CREBBPBIRC5PDGFRB
SCHEMBL4519717 0.86 NR2F2 (0.39) NR2F2BRD4CREBBPBIRC5PDGFRB
SCHEMBL4403655 0.86 BIRC5 (0.44) NR2F2BRD4CREBBPBIRC5PDGFRB
SCHEMBL4521817 0.86 NR2F2 (0.40) NR2F2BRD4CREBBPBIRC5PDGFRB
SCHEMBL29678248 0.86 AKR1C3 (0.43) NR2F2BRD4CREBBPBIRC5PDGFRB
SCHEMBL4405493 0.86 AKR1C3 (0.43) NR2F2BRD4CREBBPBIRC5PDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230111656-A1 METHODS OF CONTROLLING OR PREVENTING INFESTATION OF SOYBEAN PLANTS BY THE PHYTOPATHOGENIC MICROORGANISM CORYNESPORA CASSIICOLA SYNGENTA CROP PROTECTION AG (CH) 2023-04-13 US claimed
EP-4117436-A1 METHODS OF CONTROLLING OR PREVENTING INFESTATION OF PLANTS BY THE PHYTOPATHOGENIC MICROORGANISM CORYNESPORA CASSIICOLA Syngenta Crop Protection AG (CH) 2023-01-18 EP claimed
WO-2021180974-A1 METHODS OF CONTROLLING OR PREVENTING INFESTATION OF PLANTS BY THE PHYTOPATHOGENIC MICROORGANISM CORYNESPORA CASSIICOLA SYNGENTA CROP PROTECTION AG (CH) 2021-09-16 WO claimed
US-20170094971-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLICATION OF SAME MITSUI CHEMICALS AGRO, INC. (JP) 2017-04-06 US claimed
EP-3150069-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLYING THE SAME Mitsui Chemicals Agro, Inc. (JP) 2017-04-05 EP claimed
EP-3119200-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLICATION OF SAME Mitsui Chemicals Agro, Inc. (JP) 2017-01-25 EP claimed
WO-2015141867-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLICATION OF SAME MITSUI CHEMICALS AGRO, INC. (JP) 2015-09-24 WO claimed
EP-1736471-B1 3-(DIHYDRO(TETRAHYDRO)ISOQUINOLIN-1-YL)QUINOLINES MITSUI CHEMICALS AGRO INC (JP) 2014-01-08 EP claimed
EP-2103214-B1 USE OF QUINOLINE COMPOUNDS OR SALTS THEREOF AS ACTIVE INGREDIENTS IN SOIL- OR SEED-TREATING AGENTS AND METHOD FOR CONTROL OF PLANT DISEASE MITSUI CHEMICALS AGRO INC (JP) 2013-10-23 EP claimed
CN-101562975-B Soil treatment agent or seed treatment agent containing quinoline compound or salt thereof as active ingredient, and method for controlling plant disease using same SANKYO AGRO CO LTD 2013-10-23 CN claimed
EP-2517562-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES BY APPLYING THE COMPOSITION Mitsui Chemicals Agro, Inc. (JP) 2012-10-31 EP claimed
CN-102665414-A Plant disease control composition and method for controlling plant disease using same MITSUI CHEMICALS AGRO INC 2012-09-12 CN claimed
US-20090325998-A1 SOIL TREATING AGENT OR SEED TREATING AGENT COMPRISING QUINOLINE COMPOUNDS OR SALTS THEREOF AS ACTIVE INGREDIENT,OR METHOD FOR PREVENTING PLANT DISEASES BY USING THE SAME MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2009-12-31 US claimed
US-7632783-B2 fungicides, pesticides for protecting rice crop, tomatoes, cucumbers and green beans; 3-(5-fluoro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)quinoline MITSUI CHEMICALS AGRO, INC. (JP) 2009-12-15 US claimed
CN-100556904-C 3- (dihydro (tetrahydro) isoquinolin-1-yl) quinoline compounds SANKYO AGRO CO LTD (JP) 2009-11-04 CN claimed
CN-101562975-A Soil treatment agent or seed treatment agent containing quinoline compound or salt thereof as active ingredient, and method for controlling plant disease using same SANKYO AGRO CO LTD (JP) 2009-10-21 CN claimed
EP-2103214-A1 SOIL- OR SEED-TREATING AGENT COMPRISING QUINOLINE COMPOUND OR SALT THEREOF AS ACTIVE INGREDIENT, OR METHOD FOR CONTROL OF PLANT DISEASE USING THE SAME Sankyo Agro Company, Limited (JP) 2009-09-23 EP claimed
US-20080275242-A1 3-(Dihydro(Tetrahydro)Isoquinolin-1-Yl)Quinoline Compound MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2008-11-06 US claimed
CN-1910172-A 3- (dihydro (tetrahydro) isoquinolin-1-yl) quinoline compounds SANKYO AGRO CO LTD (JP) 2007-02-07 CN claimed
EP-1736471-A1 3-(DIHYDRO(TETRAHYDRO)ISOQUINOLIN-1-YL)QUINOLINES Sankyo Agro Company, Limited (JP) 2006-12-27 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170094971-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLICATION OF SAME BROX, HAX1, CHRM1 NR2F2 3620/4885BRD4 427/4885CREBBP 4714/4885
US-20080275242-A1 3-(Dihydro(Tetrahydro)Isoquinolin-1-Yl)Quinoline Compound QTRT1, RABL3, RECQL NR2F2 2146/4885BRD4 866/4885CREBBP 3955/4885
US-20090325998-A1 SOIL TREATING AGENT OR SEED TREATING AGENT COMPRISING QUINOLINE COMPOUNDS OR SALTS THEREOF AS ACTIVE INGREDIENT,OR METHOD FOR PREVENTING PLANT DISEASES BY USING THE SAME RABL3, H1-3, RECQL NR2F2 2046/4885BRD4 922/4885CREBBP 2655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.