SCHEMBL2326548

SCHEMBL2326548

COC(=O)C(CCSC)NC(=O)c1ccccc1OC

nearest known ligand 0.69

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.66
RAB9A P51151 1/20 0.64
TAS1R3 Q7RTX0 2/20 0.62
TAS1R1 Q7RTX1 2/20 0.62
L3MBTL1 Q9Y468 2/20 0.57
CNR1 P21554 2/20 0.53
CNR2 P34972 2/20 0.53
FNTA P49354 1/20 0.53
FNTB P49356 1/20 0.53
HPGD P15428 2/20 0.53
CYP3A4 P08684 1/20 0.52
CYP2C19 P33261 1/20 0.52
CTSD P07339 1/20 0.51
ALDH1A1 P00352 1/20 0.51
HTT P42858 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2326551 1.00 KMT2A (0.66) KMT2ARAB9ATAS1R3TAS1R1L3MBTL1
SCHEMBL2328054 0.91 KMT2A (0.62) KMT2ARAB9ATAS1R3TAS1R1L3MBTL1
SCHEMBL2328058 0.91 KMT2A (0.62) KMT2ARAB9ATAS1R3TAS1R1L3MBTL1
SCHEMBL2327144 0.90 KMT2A (0.66) KMT2ARAB9AL3MBTL1FNTAFNTB
SCHEMBL2327147 0.90 KMT2A (0.66) KMT2ARAB9AL3MBTL1FNTAFNTB
SCHEMBL2332534 0.89 KMT2A (0.60) KMT2ARAB9ATAS1R3TAS1R1L3MBTL1
SCHEMBL2332541 0.89 KMT2A (0.60) KMT2ARAB9ATAS1R3TAS1R1L3MBTL1
SCHEMBL2330662 0.88 CTSD (0.55) KMT2ARAB9ATAS1R3TAS1R1L3MBTL1
SCHEMBL2330660 0.88 CTSD (0.55) KMT2ARAB9ATAS1R3TAS1R1L3MBTL1
SCHEMBL2329474 0.84 FNTA (0.63) KMT2ATAS1R3TAS1R1L3MBTL1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2356979-B1 ANTI-WRINKLE AGENTS POLA CHEM IND INC (JP) 2017-10-25 EP disclosed
EP-3173063-A1 ANTI-WRINKLE AGENTS Pola Chemical Industries Inc. (JP) 2017-05-31 EP disclosed
EP-2356979-A1 ANTI-WRINKLE AGENTS Pola Chemical Industries Inc. (JP) 2011-08-17 EP disclosed