Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HMGCR | P04035 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19787617 | 0.81 | ALDH1A1 (0.33) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL25530283 | 0.78 | — | — | |
| SCHEMBL14380221 | 0.77 | GRM4 (0.30) | — | |
| SCHEMBL20635493 | 0.77 | TSHR (0.35) | ALDH1A1TSHR | |
| SCHEMBL23267555 | 0.75 | ALDH1A1 (0.36) | ALDH1A1TSHR | |
| SCHEMBL19706366 | 0.74 | CES2 (0.35) | — | |
| SCHEMBL16671676 | 0.73 | — | — | |
| SCHEMBL102085 | 0.73 | — | — | |
| SCHEMBL13316716 | 0.72 | ALDH1A1 (0.47) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL12463880 | 0.70 | ALDH1A1 (0.33) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024020221-A1 | MODULATORS OF TYK2 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2024-01-25 | — | — | WO | disclosed |
| WO-2021077010-A1 | BIFUNCTIONAL MOLECULES CONTAINING AN E3 UBIQUITINE LIGASE BINDING MOIETY LINKED TO A BCL6 TARGETING MOIETY | ARVINAS OPERATIONS, INC. (US) | 2021-04-22 | — | — | WO | disclosed |