⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10074939 | 0.88 | L3MBTL1 (0.31) | — | |
| SCHEMBL19787617 | 0.80 | ALDH1A1 (0.33) | — | |
| SCHEMBL23984438 | 0.79 | — | — | |
| SCHEMBL19706366 | 0.78 | CES2 (0.35) | — | |
| SCHEMBL22013342 | 0.78 | GRM4 (0.31) | — | |
| SCHEMBL23267828 | 0.78 | ALDH1A1 (0.32) | — | |
| SCHEMBL14380221 | 0.76 | GRM4 (0.30) | — | |
| SCHEMBL20635493 | 0.76 | TSHR (0.35) | — | |
| SCHEMBL502971 | 0.75 | ALDH1A1 (0.32) | — | |
| SCHEMBL27415630 | 0.74 | HMGCR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159491-A1 | Antimicrobial Compounds and Methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-05-25 | — | — | US | disclosed |
| US-20230151074-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-05-18 | — | — | US | disclosed |
| US-9284362-B2 | α/β-peptide mimics of Z-domain peptides | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2016-03-15 | — | — | US | disclosed |
| US-20150203555-A1 | ALPHA/BETA-PEPTIDE MIMICS OF Z-DOMAIN PEPTIDES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-07-23 | — | — | US | disclosed |
| US-20130231260-A1 | POLYMER SCAFFOLDS FOR ASSAY APPLICATIONS | NVS Technologies, Inc. (US) | 2013-09-05 | — | — | US | disclosed |