SCHEMBL2327142

SCHEMBL2327142

C=CCNC(=O)C=C.C=CCNCCOC(=O)C(=C)C.C=CCOC(=O)C(=C)C.C=CCOC(=O)C(=C)C

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.35
TSHR P16473 4/20 0.34
KDM4E B2RXH2 3/20 0.32
ZDHHC20 Q5W0Z9 1/20 0.31
ZDHHC2 Q9UIJ5 1/20 0.31
ALDH1A1 P00352 2/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
POLB P06746 1/20 0.31
MAPK1 P28482 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
USP2 O75604 1/20 0.31
HTT P42858 1/20 0.30
MAPT P10636 1/20 0.30
CACNA1B Q00975 1/20 0.30
APBA1 Q02410 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278238 0.85 THRB (0.46) THRBTSHRKDM4EALDH1A1SMN1; SMN2
SCHEMBL4290358 0.83 ALDH1A1 (0.32) TSHRKDM4EZDHHC20ZDHHC2ALDH1A1
SCHEMBL4945281 0.80 TSHR (0.41) THRBTSHRKDM4EALDH1A1SMN1; SMN2
SCHEMBL18866785 0.79 THRB (0.41) THRBTSHRZDHHC20ZDHHC2ALDH1A1
SCHEMBL3818410 0.79 THRB (0.46) THRBTSHRZDHHC20ZDHHC2ALDH1A1
SCHEMBL23031288 0.78 THRB (0.40) THRBTSHRALDH1A1POLBTDP1
SCHEMBL4282275 0.78 THRB (0.30) THRB
SCHEMBL9696561 0.75 THRB (0.57) THRBTSHRKDM4EALDH1A1POLB
SCHEMBL23031233 0.75 THRB (0.42) THRBTSHRKDM4EALDH1A1SMN1; SMN2
SCHEMBL586950 0.75 THRB (0.42) THRBTSHRALDH1A1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7256168-B2 Washing or cleaning agent shaped bodies HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-08-14 US claimed
US-20040053808-A1 Washing or cleaning agent shaped bodies HENKEL AG & CO. KGAA (DE) 2004-03-18 US claimed
US-6340664-B1 FOR WASHING TEXTILES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (KGAA) (DE) 2002-01-22 US claimed
EP-3409754-A1 COATED CITRIC ACID PARTICLES IN CLEANING COMPOSITIONS Dalli-Werke GmbH & Co. KG (DE) 2018-12-05 EP disclosed
EP-2190968-B1 COATED DETERGENT COMPOSITION AND MANUFACTURE PROCESS DALLI-WERKE GMBH & CO KG (DE) 2017-06-21 EP disclosed
US-20160340623-A1 SANITARY SELF-ADHESIVE PRODUCTS EURVEST SA (BE) 2016-11-24 US disclosed
EP-2045319-B1 Coated detergent composition and manufacture process DALLI WERKE GMBH & CO KG (DE) 2015-12-02 EP disclosed
WO-2015120886-A1 SANITARY SELF-ADHESIVE PRODUCTS EURVEST SA (BE) 2015-08-20 WO disclosed
EP-2196531-B1 Polymer coated detergent tablet DALLI WERKE GMBH & CO KG (DE) 2014-09-03 EP disclosed
US-8334249-B2 Coated detergent composition and manufacture process DALLI-WERKE GMBH & CO. KG (DE) 2012-12-18 US disclosed
US-7993484-B2 Two-component structural adhesive having high initial adhesion Henekl AG & Co. KGaA (DE) 2011-08-09 US disclosed
WO-2009036914-A1 COATED DETERGENT COMPOSITION AND MANUFACTURE PROCESS DALLI-WERKE GMBH & CO. KG (DE) 2009-03-26 WO disclosed
WO-2008034594-A1 COATED DETERGENT COMPOSITIONS AND MANUFACTURE PROCESS DALLI-WERKE GMBH & CO. KG (DE) 2008-03-27 WO disclosed
EP-1903099-A1 Coated detergent compositions and manufacture process Dalli-Werke GmbH & Co. KG (DE) 2008-03-26 EP disclosed
US-7256168-B2 Washing or cleaning agent shaped bodies HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2007-08-14 US disclosed
US-20060157196-A1 Two-component structural adhesive having high initial adhesion HENKEL AG & CO. KGAA (DE) 2006-07-20 US disclosed
US-7041632-B2 Perfumed detergent shaped bodies HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2006-05-09 US disclosed
US-20040053808-A1 Washing or cleaning agent shaped bodies HENKEL AG & CO. KGAA (DE) 2004-03-18 US disclosed
US-20030166493-A1 Shaped bodies with subsequent addition of surfactants HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2003-09-04 US disclosed
US-20030166492-A1 Perfumed detergent shaped bodies HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2003-09-04 US disclosed