SCHEMBL232764

SCHEMBL232764

[NH]C(=O)Nc1ccncc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MDM2 Q00987 1/20 0.67
KDM4E B2RXH2 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
TAAR1 Q96RJ0 2/20 0.57
GAA P10253 1/20 0.54
KMT2A Q03164 3/20 0.53
JAK2 O60674 3/20 0.53
TYK2 P29597 3/20 0.53
MEN1 O00255 2/20 0.53
BCHE P06276 1/20 0.52
POLB P06746 1/20 0.52
STAT3 P40763 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
NT5E P21589 1/20 0.50
EPHX1 P07099 1/20 0.50
ALDH1A1 P00352 2/20 0.49
JAK1 P23458 2/20 0.48
ROCK2 O75116 1/20 0.48
ROCK1 Q13464 1/20 0.48
CYP3A4 P08684 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10020286 0.80 MDM2 (1.00) MDM2KDM4EL3MBTL1TAAR1GAA
SCHEMBL1234281 0.78 MDM2 (0.70) MDM2KDM4EL3MBTL1TAAR1GAA
SCHEMBL31668740 0.78 MDM2 (0.95) MDM2KDM4EL3MBTL1TAAR1GAA
SCHEMBL6061912 0.78 MDM2 (0.70) MDM2KDM4EL3MBTL1TAAR1GAA
SCHEMBL19774543 0.77 KDM4E (0.80) MDM2KDM4EL3MBTL1GAAKMT2A
SCHEMBL1466506 0.76 MDM2 (0.54) MDM2KDM4EL3MBTL1TAAR1GAA
SCHEMBL48610 0.76 TSHR (0.69) MDM2KDM4EL3MBTL1TAAR1GAA
SCHEMBL5417314 0.76 MDM2 (0.67) MDM2KDM4EL3MBTL1TAAR1GAA
SCHEMBL230957 0.76 MDM2 (0.67) MDM2KDM4EL3MBTL1TAAR1GAA
SCHEMBL9297607 0.76 MDM2 (0.67) MDM2KDM4EL3MBTL1TAAR1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 203 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12030790-B2 Method for removing fluorine-containing compound from waste water DAIKIN INDUSTRIES, LTD. (JP) 2024-07-09 US disclosed
CN-118221526-A Hydrocarbon-containing carboxylic acid, hydrocarbon-containing sulfonic acid, hydrocarbon-containing sulfate or salts thereof, surfactant 大金工业株式会社 2024-06-21 CN disclosed
CN-116134060-B Method for producing aqueous dispersion of fluoroelastomer, and aqueous dispersion 大金工业株式会社 2024-06-18 CN disclosed
CN-118146427-A Method for producing fluorine-containing polymer, polytetrafluoroethylene composition, and polytetrafluoroethylene powder 大金工业株式会社 2024-06-07 CN disclosed
CN-118146601-A Method for producing fluorine-containing polymer, polytetrafluoroethylene composition, and polytetrafluoroethylene powder 大金工业株式会社 2024-06-07 CN disclosed
US-20240166777-A1 PRODUCTION METHOD OF HIGH-PURITY FLUOROPOLYMER-CONTAINING COMPOSITION AND HIGH-PURITY FLUOROPOLYMER-CONTAINING COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 2024-05-23 US disclosed
CN-118043130-A Method for producing hollow fine particles, phase-separated fine particles, aqueous dispersion, and composition 大金工业株式会社 2024-05-14 CN disclosed
CN-118027319-A Fluorine-containing polymer 大金工业株式会社 2024-05-14 CN disclosed
EP-4365211-A1 METHOD FOR PRODUCING HIGH-PURITY FLUOROPOLYMER-CONTAINING COMPOSITION, AND HIGH-PURITY FLUOROPOLYMER-CONTAINING COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 2024-05-08 EP disclosed
EP-4365212-A1 METHOD FOR PRODUCING FLUOROPOLYMER COMPOSITION, AND FLUOROPOLYMER COMPOSITION DAIKIN INDUSTRIES, LTD. (JP) 2024-05-08 EP disclosed
US-20110163283-A1 AZO COMPOUNDS, AZO PIGMENTS, PIGMENT DISPERSION, COLORING COMPOSITION, AND INK FOR INKJET RECORDING FUJIFILM CORPORATION (JP) 2011-07-07 US disclosed
US-20110143270-A1 AZO COMPOUND, AZO PIGMENT, PIGMENT DISPERSION, COLORING COMPOSITION, INK FOR INKJET RECORDING, COLORING COMPOSITION FOR COLOR FILTER, COLOR FILTER, AND PROCESS FOR PREPARING A COLORING COMPOSITION FOR COLOR FILTER FUJIFILM CORPORATION (JP) 2011-06-16 US disclosed
EP-2325264-A1 AZO COMPOUND, AZO PIGMENT, PIGMENT DISPERSION, COLOR COMPOSITION AND INK FOR INKJET RECORDING FUJIFILM Corporation (JP) 2011-05-25 EP disclosed
EP-2319890-A1 AZO COMPOUND, AZO PIGMENT, PIGMENT DISPERSION, COLOR COMPOSITION, INKJET RECORDING INK, COLOR COMPOSITION FOR COLOR FILTER, COLOR FILTER, AND METHOD FOR PREPARING COLOR COMPOSITION FOR COLOR FILTER FUJIFILM Corporation (JP) 2011-05-11 EP disclosed
US-20110071141-A1 Pesticidial Condensed-Ring Aryl Compounds BAYER CROPSCIENCE AG 2011-03-24 US disclosed
CN-101970403-A Insecticidal fused ring aryl compounds BAYER CROPSCIENCE AG 2011-02-09 CN disclosed
EP-2254863-A1 PESTICIDAL CONDENSED - RING ARYL COMPOUNDS Bayer CropScience AG (DE) 2010-12-01 EP disclosed
WO-2009112275-A1 PESTICIDAL CONDENSED - RING ARYL COMPOUNDS BAYER CROPSCIENCE AG (DE) 2009-09-17 WO disclosed
EP-1147079-A2 BETA-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS Bayer Aktiengesellschaft (DE) 2001-10-24 EP disclosed
WO-2000041469-A2 β-PHENYLALANINE DERIVATIVES AS INTEGRIN ANTAGONISTS BAYER AKTIENGESELLSCHAFT (DE) 2000-07-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110071141-A1 Pesticidial Condensed-Ring Aryl Compounds DDT, PRDX4, CYP4X1 MDM2 1821/4885KDM4E 825/4885L3MBTL1 1106/4885
US-20110163283-A1 AZO COMPOUNDS, AZO PIGMENTS, PIGMENT DISPERSION, COLORING COMPOSITION, AND INK FOR INKJET RECORDING RB1, IK, TYR MDM2 3711/4885KDM4E 159/4885L3MBTL1 2410/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.