Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | TYK2 | P29597 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9297614 | 0.78 | MDM2 (0.56) | MDM2EPHX1KDM4EL3MBTL1TAAR1 | |
| SCHEMBL526209 | 0.76 | ALDH1A1 (0.60) | MDM2EPHX1KDM4EL3MBTL1TAAR1 | |
| SCHEMBL222140 | 0.76 | MDM2 (0.54) | MDM2EPHX1KDM4EL3MBTL1TAAR1 | |
| SCHEMBL232764 | 0.76 | MDM2 (0.67) | MDM2EPHX1KDM4EL3MBTL1TAAR1 | |
| SCHEMBL330186 | 0.75 | ALDH1A1 (0.64) | EPHX1KDM4EMEN1KMT2AGAA | |
| SCHEMBL23293647 | 0.74 | PHGDH (0.61) | MDM2EPHX1KDM4EL3MBTL1TAAR1 | |
| Hydrochloric Acid SCHEMBL31091389 | 0.74 | ALDH1A1 (0.58) | MDM2EPHX1KDM4EL3MBTL1TAAR1 | |
| SCHEMBL1465824 | 0.74 | ATG4B (0.56) | KDM4EKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL16566469 | 0.73 | ALDH1A1 (0.74) | EPHX1TAAR1MEN1KMT2AGAA | |
| SCHEMBL4399385 | 0.73 | EPHX1 (0.52) | MDM2EPHX1KDM4EL3MBTL1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2440527-A1 | PYRIDINYL DERIVATIVES AS INHIBITORS OF ENZYME NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE | Topo Target A/S (DK) | 2012-04-18 | — | — | EP | disclosed |
| US-20110071141-A1 | Pesticidial Condensed-Ring Aryl Compounds | BAYER CROPSCIENCE AG | 2011-03-24 | — | — | US | disclosed |
| EP-2254863-A1 | PESTICIDAL CONDENSED - RING ARYL COMPOUNDS | Bayer CropScience AG (DE) | 2010-12-01 | — | — | EP | disclosed |
| US-20090233960-A1 | Kinase Inhibitors | DEVGEN NV (BE) | 2009-09-17 | — | — | US | disclosed |
| WO-2009112275-A1 | PESTICIDAL CONDENSED - RING ARYL COMPOUNDS | BAYER CROPSCIENCE AG (DE) | 2009-09-17 | — | — | WO | disclosed |
| EP-1934181-A2 | KINASE INHIBITORS | Devgen NV (BE) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007042321-A2 | KINASE INHIBITORS | DEVGEN N.V. (BE) | 2007-04-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071141-A1 | Pesticidial Condensed-Ring Aryl Compounds | DDT, PRDX4, CYP4X1 | MDM2 1821/4885EPHX1 763/4885KDM4E 825/4885 |
| US-20090233960-A1 | Kinase Inhibitors | ROCK1, MAP3K1, MAP3K11 | MDM2 1439/4885EPHX1 3383/4885KDM4E 4294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.