Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | BID | P55957 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8857520 | 0.94 | CYP3A4 (0.45) | LIPGSLC6A2SLC6A4SLC6A3TLR8 | |
| SCHEMBL9512782 | 0.85 | SLC6A4 (0.49) | SLC6A2SLC6A4SLC6A3MCL1CYP3A4 | |
| Water SCHEMBL28085363 | 0.85 | LIPG (0.67) | LIPGNR1H2NR1H3ALOX5PTGS2 | |
| Iodide SCHEMBL29040645 | 0.85 | LIPG (0.67) | LIPGNR1H2NR1H3ALOX5PTGS2 | |
| SCHEMBL30037094 | 0.85 | LIPG (0.65) | LIPGNR1H2NR1H3ALOX5PTGS2 | |
| SCHEMBL82794 | 0.85 | LIPG (0.65) | LIPGNR1H2NR1H3ALOX5PTGS2 | |
| SCHEMBL8085404 | 0.83 | LIPG (0.59) | LIPGNR1H2NR1H3ALOX5PTGS2 | |
| SCHEMBL1343771 | 0.83 | LIPG (0.69) | LIPGNR1H2NR1H3ALOX5PTGS2 | |
| SCHEMBL2511612 | 0.83 | LIPG (0.69) | LIPGNR1H2NR1H3ALOX5PTGS2 | |
| SCHEMBL15809821 | 0.83 | LIPG (0.69) | LIPGNR1H2NR1H3ALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3189041-B1 | TETRAHYDROISOQUINOLINE DERIVED PRMT5-INHIBITORS | CTXT PTY LTD (AU) | 2021-04-28 | — | — | EP | disclosed |