SCHEMBL23280830

SCHEMBL23280830

Cc1cc2sc3c(sc4c5sc(N)cc5sc43)c2s1

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21515261 0.98 PKM (0.40) PKMNPSR1RXFP1
SCHEMBL12775254 0.87 PKM (0.47) PKMNPSR1RXFP1
SCHEMBL20173340 0.87 PKM (0.47) PKMNPSR1RXFP1
SCHEMBL12775257 0.84 PKM (0.48) PKMNPSR1RXFP1
SCHEMBL23280862 0.84 GPR35 (0.32)
SCHEMBL18544411 0.80 PKM (0.37) PKMNPSR1RXFP1
SCHEMBL12681760 0.77 GPR35 (0.39)
SCHEMBL120586 0.77 PKM (0.50) PKMNPSR1RXFP1
SCHEMBL18965745 0.75 BACE1 (0.36) PKMNPSR1RXFP1
SCHEMBL20288333 0.74 PKM (0.41) PKMNPSR1RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3551635-B1 THIENO-INDENO-MONOMERS AND POLYMERS BASF SE (DE) 2021-04-28 EP disclosed