Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RBP4 | P02753 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | DKK1 | O94907 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL345939 | 0.84 | KDM1A (0.44) | SLC6A7HDAC6 | |
| SCHEMBL346015 | 0.84 | ADRB1 (0.58) | KMT2ARBP4ADRB1CHRM4SLC6A7 | |
| SCHEMBL2328242 | 0.83 | RBP4 (0.40) | KMT2ARBP4ADRB1CHRM4MAPK1 | |
| SCHEMBL345329 | 0.82 | ADRB1 (0.52) | KMT2ARBP4ADRB1CHRM4SLC6A7 | |
| SCHEMBL344771 | 0.77 | ADRB1 (0.55) | KMT2ARBP4ADRB1CHRM4SLC6A7 | |
| SCHEMBL2834267 | 0.77 | ADRB1 (0.61) | KMT2ARBP4ADRB1CHRM4SLC6A7 | |
| SCHEMBL14622839 | 0.71 | ADORA2A (0.43) | HTR1A | |
| SCHEMBL345280 | 0.71 | DRD4 (0.46) | CHRM4KCNH2HTR1AHDAC6KDM4E | |
| SCHEMBL13990826 | 0.71 | ADRB1 (0.59) | KMT2ARBP4ADRB1CHRM4SLC6A7 | |
| SCHEMBL4765939 | 0.69 | CCR2 (0.53) | KMT2ARBP4ADRB1CHRM4SLC6A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2356108-A1 | CARBAMATE DERIVATIVES OF ALKYL-HETEROCYCLES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2011-08-17 | — | — | EP | disclosed |
| WO-2010055267-A1 | CARBAMATE DERIVATIVES OF ALKYL-HETEROCYCLES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-05-20 | — | — | WO | disclosed |