⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21044598 | 0.73 | GLB1 (0.34) | — | |
| SCHEMBL26382608 | 0.70 | — | — | |
| SCHEMBL21044599 | 0.66 | — | — | |
| SCHEMBL21044604 | 0.65 | TP53 (0.34) | — | |
| SCHEMBL9491033 | 0.64 | FDPS (0.38) | — | |
| SCHEMBL23345386 | 0.64 | — | — | |
| SCHEMBL9172321 | 0.64 | — | — | |
| SCHEMBL17275173 | 0.62 | — | — | |
| SCHEMBL18930722 | 0.61 | ACHE (0.46) | — | |
| SCHEMBL69489 | 0.60 | TSHR (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3812379-A1 | CRYSTALLINE FORM OF A N-(PYRAZOL-4-YL)SULFONYL-6-(PYRAZOL-1-YL)-2-(PYRROLIDIN-1-YL)PYRIDINE-3-CARBOXAMIDE FOR TREATING CYSTIC FIBROSIS | Vertex Pharmaceuticals Incorporated (US) | 2021-04-28 | — | — | EP | disclosed |