Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1189331 | 0.81 | GAA (0.39) | ACHEMAPTGAAELANEFUCA1 | |
| SCHEMBL16080213 | 0.81 | ACHE (0.45) | ACHEMAPTFUCA1 | |
| SCHEMBL23377484 | 0.81 | FUCA1 (0.45) | MAPTGAAOPRK1ELANEFUCA1 | |
| SCHEMBL30748878 | 0.81 | GAA (0.39) | ACHEMAPTGAAELANEFUCA1 | |
| SCHEMBL17069522 | 0.80 | MEN1 (0.39) | ACHEGAAELANEFUCA1 | |
| SCHEMBL21438350 | 0.80 | GAA (0.38) | ACHEMAPTGAAELANEFUCA1 | |
| SCHEMBL21468783 | 0.79 | MEN1 (0.38) | ACHEMAPTGAAELANEFUCA1 | |
| SCHEMBL21438880 | 0.79 | GAA (0.37) | ACHEMAPTGAAELANEFUCA1 | |
| SCHEMBL19111473 | 0.79 | JAK1 (0.40) | ACHEGAAELANEFUCA1HRH4 | |
| SCHEMBL17063291 | 0.79 | MEN1 (0.41) | MAPTGAAFUCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884847-B2 | Indazole retinoic acid receptor-related orphan receptor modulators and uses thereof | INNOV17 LLC (US) | 2018-02-06 | — | — | US | disclosed |
| US-20170298060-A1 | PYRROLOPYRIDINE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF | INNOV17 LLC | 2017-10-19 | — | — | US | disclosed |
| US-9771374-B2 | Benzimidazole retinoic acid receptor-related orphan receptor modulators and uses thereof | INNOV17 LLC (US) | 2017-09-26 | — | — | US | disclosed |
| US-20170217956-A1 | AZAINDOLE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF | INNOV17 LLC (US) | 2017-08-03 | — | — | US | disclosed |
| US-9701663-B2 | Sulfonamide retinoic acid receptor-related orphan receptor modulators and uses thereof | INNOV17 LLC (US) | 2017-07-11 | — | — | US | disclosed |
| US-20170190712-A1 | BENZIMIDAZOLE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF | INNOV17 LLC | 2017-07-06 | — | — | US | disclosed |
| US-20170158669-A1 | INDAZOLE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF | INNOV17 LLC | 2017-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190712-A1 | BENZIMIDAZOLE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF | RARB, RARA, RARG | ACHE 3857/4885MAPT 4268/4885GAA 329/4885 |
| US-20170298060-A1 | PYRROLOPYRIDINE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF | RARB, RARA, RARG | ACHE 4485/4885MAPT 4078/4885GAA 1083/4885 |
| US-20170158669-A1 | INDAZOLE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF | RXRA, RXRB, RARB | ACHE 3460/4885MAPT 3340/4885GAA 1121/4885 |
| US-20170217956-A1 | AZAINDOLE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF | RARA, RARB, RARG | ACHE 3918/4885MAPT 4277/4885GAA 1376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.