Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23287003 | 0.89 | PTGER4 (0.53) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL23286926 | 0.88 | PTGER4 (0.56) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL23287036 | 0.85 | PTGER4 (0.47) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL23273555 | 0.85 | PTGER4 (0.57) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL23287173 | 0.82 | PTGER4 (0.70) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL23286252 | 0.81 | MAPT (0.60) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL29738069 | 0.81 | MAPT (0.60) | PTGER4ALDH1A1MAPTRAB9AHCAR3 | |
| SCHEMBL23287088 | 0.78 | SLC7A5 (0.40) | PTGER4ALDH1A1MAPTALOX15HPGD | |
| SCHEMBL23287050 | 0.76 | ALOX15 (0.39) | PTGER4ALDH1A1MAPTRAB9AALOX15 | |
| SCHEMBL24083653 | 0.75 | ALOX15 (0.43) | ALDH1A1RAB9AALOX15SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702404-B2 | GLP-1R modulating compounds | GILEAD SCIENCES, INC. (US) | 2023-07-18 | — | — | US | disclosed |
| US-20210171499-A1 | GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. | 2021-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11702404-B2 | GLP-1R modulating compounds | GLP1R, GIPR, GPR119 | PTGER4 996/4885ALDH1A1 3556/4885MAPT 3314/4885 |
| US-20210171499-A1 | GLP-1R MODULATING COMPOUNDS | GLP1R, GIPR, GPR119 | PTGER4 996/4885ALDH1A1 3556/4885MAPT 3314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.