Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 7/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23274021 | 0.84 | NUDT1 (0.49) | MAOBFFAR1MAOANUDT1 | |
| SCHEMBL27383565 | 0.78 | IDO1 (0.51) | IDO1PIN1MAOBMAOALMNA | |
| SCHEMBL8965946 | 0.78 | IDO1 (0.51) | IDO1PIN1MAOBFFAR1MAOA | |
| SCHEMBL5096517 | 0.74 | MAOB (0.62) | IDO1MAOBMAOA | |
| SCHEMBL12113611 | 0.72 | ALDH1A1 (0.41) | LMNA | |
| SCHEMBL14611352 | 0.72 | CYP2D6 (0.58) | IDO1PIN1MAOBMAOAHTR1A | |
| SCHEMBL23316746 | 0.71 | LOXL2 (0.59) | IDO1PIN1MAOBMAOALMNA | |
| SCHEMBL30931616 | 0.71 | LOXL2 (0.59) | IDO1PIN1MAOBMAOALMNA | |
| SCHEMBL22874550 | 0.70 | MAOB (0.66) | IDO1MAOBMAOA | |
| SCHEMBL8488996 | 0.69 | MAOB (0.60) | IDO1PIN1MAOBMAOALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021080013-A1 | INHIBITORS OF TREK (TWIK RELATED K+ CHANNELS) CHANNEL FUNCTION | ONO PHARMACEUTICAL CO., LTD. (JP) | 2021-04-29 | — | — | WO | disclosed |