Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.67 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16384292 | 0.96 | CASP2 (0.73) | CASP2NAAAFAAHMEN1KMT2A | |
| SCHEMBL19880209 | 0.94 | CASP2 (0.77) | CASP2NAAAFAAHMEN1KMT2A | |
| SCHEMBL17070055 | 0.94 | CASP2 (0.77) | CASP2NAAAFAAHMEN1KMT2A | |
| SCHEMBL14576993 | 0.91 | CASP2 (0.78) | CASP2NAAAFAAHMEN1KMT2A | |
| SCHEMBL16384289 | 0.89 | CASP2 (0.59) | CASP2NAAAFAAHMEN1KMT2A | |
| SCHEMBL21761818 | 0.88 | FAAH (0.65) | CASP2NAAAFAAHDNM1LPAR1 | |
| SCHEMBL19935560 | 0.88 | FAAH (0.55) | CASP2NAAAFAAHMEN1KMT2A | |
| SCHEMBL12583601 | 0.86 | CASP2 (0.59) | CASP2NAAAFAAHMEN1KMT2A | |
| SCHEMBL10038842 | 0.86 | CASP2 (0.48) | CASP2NAAAFAAHMEN1KMT2A | |
| SCHEMBL7537764 | 0.86 | CASP2 (0.86) | CASP2NAAAFAAHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223315-A2 | METHOD FOR SYNTHESIS OF REACTIVE CONJUGATE CLUSTERS | Ionis Pharmaceuticals, Inc. (US) | 2023-08-09 | — | — | EP | disclosed |
| EP-3811977-A1 | METHOD FOR SYNTHESIS OF REACTIVE CONJUGATE CLUSTERS | Ionis Pharmaceuticals, Inc. (US) | 2021-04-28 | — | — | EP | disclosed |