Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23288566 | 0.85 | FFAR1 (0.41) | ALOX5FFAR1KMT2AALDH1A1PTGES | |
| SCHEMBL23288560 | 0.78 | ALDH1A1 (0.36) | ALOX5FFAR1KMT2AALDH1A1MEN1 | |
| SCHEMBL23288561 | 0.76 | FFAR1 (0.43) | ALOX5FFAR1KMT2AALDH1A1PTGES | |
| SCHEMBL23288559 | 0.74 | FFAR1 (0.41) | FFAR1KMT2AALDH1A1MEN1PTGES | |
| SCHEMBL23288563 | 0.74 | ALDH1A1 (0.42) | KMT2AALDH1A1MEN1PTGESACACB | |
| SCHEMBL23288506 | 0.71 | ALOX5 (0.56) | ALOX5KMT2AALDH1A1 | |
| SCHEMBL23288502 | 0.71 | KMT2A (0.43) | KMT2AALDH1A1MEN1PTGESACACB | |
| SCHEMBL23288524 | 0.69 | FFAR1 (0.41) | FFAR1KMT2AALDH1A1PTGESFFAR4 | |
| SCHEMBL23288525 | 0.69 | ALDH1A1 (0.46) | KMT2AALDH1A1MEN1PTGESACACB | |
| SCHEMBL23288552 | 0.67 | ALOX5 (0.50) | ALOX5KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021081315-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CRYPTOSPORIDIOSIS | THE BROAD INSTITUTE, INC. (US) | 2021-04-29 | — | — | WO | disclosed |