SCHEMBL2328864

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2323826	0.89	PIM1 (0.49)	ACVR1BATRPIM1PIM3PIM2
	SCHEMBL13834756	0.81	TDO2 (0.45)	TNKSACVR1BTGFBR1JAK2JAK1
	SCHEMBL2324168	0.81	ALK (0.42)	TNKSACVR1BTGFBR1JAK2JAK1
	SCHEMBL12440313	0.80	CYP1A2 (0.53)	MAPK14PIM1PIM3CSNK1DHRH4
	SCHEMBL19791404	0.79	MAP4K1 (0.42)	PIM1
	SCHEMBL2325237	0.78	EGFR (0.43)	JAK2JAK1TYK2JAK3WNT1
	SCHEMBL12440007	0.75	SCD (0.40)	TDO2MAPK14WNT1DYRK1ACSNK1D
	SCHEMBL2324592	0.75	LMNA (0.36)	HRH4
	SCHEMBL3241755	0.74	CNR2 (0.56)	TNKSACVR1BTGFBR1JAK2JAK1
	SCHEMBL10153132	0.74	ACVR1B (0.52)	TNKSACVR1BTGFBR1JAK2JAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.