SCHEMBL12440313

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12440069	0.90	CYP1A2 (0.46)	CYP1A2ALDH1A1CYP3A4CYP2D6HSD17B10
	SCHEMBL19791404	0.85	MAP4K1 (0.42)	CYP1A2CYP3A4CYP2D6CLK4ALOX15
	SCHEMBL12440312	0.85	GBA1 (0.45)	CYP1A2ALDH1A1CYP3A4CYP2D6HSD17B10
	SCHEMBL2324592	0.84	LMNA (0.36)	CYP1A2ALDH1A1CYP3A4CYP2D6HSD17B10
	SCHEMBL12440009	0.80	ALDH1A1 (0.38)	CYP1A2ALDH1A1CYP3A4CYP2D6HSD17B10
	SCHEMBL2328864	0.80	TNKS (0.45)	HRH4MAPK14CSNK1DPIM1PIM3
	SCHEMBL13834756	0.79	TDO2 (0.45)	CLK4MAPK14CSNK1DMET
	SCHEMBL2324168	0.78	ALK (0.42)	CLK4MET
	SCHEMBL2326924	0.78	CNR2 (0.45)	TSHRKDM4EMEN1KMT2ASMN1; SMN2
	SCHEMBL12441212	0.78	NPC1 (0.39)	CYP1A2ALDH1A1CYP3A4CYP2D6HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.