Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.55 |
| ▸ | PLK1 | P53350 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.48 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9971549 | 0.80 | S1PR1 (0.54) | RAB9ASMN1; SMN2TP53PLK1CA12 | |
| SCHEMBL19941493 | 0.80 | CA12 (0.54) | RAB9ASMN1; SMN2TP53PLK1CA12 | |
| SCHEMBL26103668 | 0.80 | HDAC6 (0.62) | — | |
| SCHEMBL14393799 | 0.79 | RAB9A (0.52) | RAB9ASMN1; SMN2TP53PLK1CA12 | |
| SCHEMBL5843831 | 0.79 | PLK1 (0.67) | RAB9ASMN1; SMN2TP53PLK1CA12 | |
| SCHEMBL17316313 | 0.78 | LMNA (0.56) | RAB9ASMN1; SMN2TP53PLK1CA12 | |
| SCHEMBL7074248 | 0.78 | PLK1 (0.57) | RAB9APLK1CA12CA1CA2 | |
| SCHEMBL8792955 | 0.77 | PLK1 (0.65) | RAB9ASMN1; SMN2TP53PLK1CA12 | |
| SCHEMBL856937 | 0.77 | PLK1 (0.55) | RAB9ASMN1; SMN2TP53PLK1CA12 | |
| SCHEMBL15307622 | 0.77 | L3MBTL1 (0.58) | RAB9ASMN1; SMN2TP53PLK1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3814343-A1 | CARDIAC SARCOMERE INHIBITORS | Cytokinetics, Inc. (US) | 2021-05-05 | — | — | EP | disclosed |