Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 20/20 | 0.73 |
| ▸ | KIT | P10721 | 2/20 | 0.55 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.55 |
| ▸ | AXL | P30530 | 1/20 | 0.55 |
| ▸ | FLT3 | P36888 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13405631 | 0.84 | CSF1R (1.00) | CSF1RKIT | |
| SCHEMBL31157967 | 0.84 | CSF1R (1.00) | CSF1RKIT | |
| SCHEMBL31157983 | 0.84 | CSF1R (1.00) | CSF1RKIT | |
| SCHEMBL23293604 | 0.83 | CSF1R (0.73) | CSF1RKITNTRK1AXLFLT3 | |
| SCHEMBL13405727 | 0.81 | CSF1R (1.00) | CSF1RKITNTRK1AXLFLT3 | |
| SCHEMBL3969306 | 0.77 | CSF1R (0.88) | CSF1RKIT | |
| SCHEMBL13439324 | 0.76 | CSF1R (0.64) | CSF1RKITNTRK1AXLFLT3 | |
| SCHEMBL13405751 | 0.76 | CSF1R (1.00) | CSF1RKIT | |
| SCHEMBL3964211 | 0.75 | CSF1R (0.73) | CSF1RKITNTRK1AXLFLT3 | |
| SCHEMBL23293311 | 0.74 | CSF1R (0.88) | CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210290784-A1 | POSITRON EMISSION TOMOGRAPHY (PET) RADIOTRACERS FOR IMAGING MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR (CSF1R) IN NEUROINFLAMMATION | THE JOHNS HOPKINS UNIVERSITY | 2021-09-23 | — | — | US | claimed |
| EP-3813890-A1 | POSITRON EMISSION TOMOGRAPHY (PET) RADIOTRACERS FOR IMAGING MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR (CSF1R) IN NEUROINFLAMMATION | The Johns Hopkins University (US) | 2021-05-05 | — | — | EP | claimed |
| CN-112638431-A | Positron Emission Tomography (PET) radiotracers for imaging macrophage colony stimulating factor 1 receptor (CSF1R) in neuroinflammation | 约翰霍普金斯大学 | 2021-04-09 | — | — | CN | claimed |
| CN-118743770-A | Positron Emission Tomography (PET) radiotracer for imaging macrophage colony stimulating factor 1 receptor (CSF 1R) in neuroinflammation | 约翰霍普金斯大学 | 2024-10-08 | — | — | CN | disclosed |
| US-20210290784-A1 | POSITRON EMISSION TOMOGRAPHY (PET) RADIOTRACERS FOR IMAGING MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR (CSF1R) IN NEUROINFLAMMATION | THE JOHNS HOPKINS UNIVERSITY | 2021-09-23 | — | — | US | disclosed |
| EP-3813890-A1 | POSITRON EMISSION TOMOGRAPHY (PET) RADIOTRACERS FOR IMAGING MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR (CSF1R) IN NEUROINFLAMMATION | The Johns Hopkins University (US) | 2021-05-05 | — | — | EP | disclosed |
| CN-112638431-A | Positron Emission Tomography (PET) radiotracers for imaging macrophage colony stimulating factor 1 receptor (CSF1R) in neuroinflammation | 约翰霍普金斯大学 | 2021-04-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210290784-A1 | POSITRON EMISSION TOMOGRAPHY (PET) RADIOTRACERS FOR IMAGING MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR (CSF1R) IN NEUROINFLAMMATION | CSF1R, CSF3R, CMKLR1 | CSF1R 1/4885KIT 315/4885NTRK1 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.