Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAP2K4 | P45985 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MAPKAPK3 | Q16644 | 2/20 | 0.36 |
| ▸ | MAPK6 | Q16659 | 2/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 8/20 | 0.34 |
| ▸ | ALPL | P05186 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23328966 | 0.86 | MAP2K4 (0.41) | MAP2K4MAPK1MAPKAPK3MAPK6HAO1 | |
| SCHEMBL23294600 | 0.84 | ALPL (0.47) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL23294286 | 0.83 | MAP2K4 (0.38) | MAP2K4MAPK1MAPKAPK3MAPK6HAO1 | |
| SCHEMBL23294606 | 0.83 | ALPL (0.49) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL23294375 | 0.81 | MAP2K4 (0.45) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL23294477 | 0.81 | MAP2K4 (0.45) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL23294305 | 0.79 | XDH (0.50) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL23294401 | 0.78 | HAO1 (0.45) | KDM4EALDH1A1HPGDMAP2K4MAPK1 | |
| SCHEMBL23294326 | 0.78 | MCL1 (0.41) | ALDH1A1HPGDMAP2K4MAPK1HAO1 | |
| SCHEMBL23294515 | 0.78 | HAO1 (0.48) | ALDH1A1MAP2K4MAPK1MAPK6HAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210128532-A1 | HETEROCYCLIC CARBOXYLATE COMPOUNDS AS GLYCOLATE OXIDASE INHIBITORS | Lilac Therapeutics, Inc. | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210128532-A1 | HETEROCYCLIC CARBOXYLATE COMPOUNDS AS GLYCOLATE OXIDASE INHIBITORS | UGDH, PGD, PNPO | KDM4E 1855/4885ALDH1A1 184/4885GLA 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.