Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | STAT3 | P40763 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | DRD4 | P21917 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9550978 | 0.90 | ALDH1A1 (0.50) | ALDH1A1CA1CA12CA9STAT3 | |
| SCHEMBL478342 | 0.90 | ALDH1A1 (0.53) | ALDH1A1CA1CA12CA9STAT3 | |
| SCHEMBL881292 | 0.90 | ALDH1A1 (0.53) | ALDH1A1CA1CA12CA9STAT3 | |
| SCHEMBL1145153 | 0.90 | ALDH1A1 (0.53) | ALDH1A1CA1CA12CA9STAT3 | |
| SCHEMBL18613994 | 0.90 | ALDH1A1 (0.53) | ALDH1A1CA1CA12CA9STAT3 | |
| SCHEMBL922407 | 0.90 | ALDH1A1 (0.53) | ALDH1A1CA1CA12CA9STAT3 | |
| SCHEMBL18644929 | 0.90 | ALDH1A1 (0.53) | ALDH1A1CA1CA12CA9STAT3 | |
| SCHEMBL12865316 | 0.90 | ALDH1A1 (0.53) | ALDH1A1CA1CA12CA9STAT3 | |
| SCHEMBL4379133 | 0.90 | ALDH1A1 (0.53) | ALDH1A1CA1CA12CA9STAT3 | |
| SCHEMBL22609426 | 0.89 | ALDH1A1 (0.49) | ALDH1A1CA1CA12CA9STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11666623-B2 | Tetramaleimide linkers and use thereof | NEWBIO THERAPEUTICS, INC. (CN) | 2023-06-06 | — | — | US | disclosed |
| US-20210128668-A1 | TETRAMALEIMIDE LINKERS AND USE THEREOF | NEWBIO THERAPEUTICS, INC. (CN) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210128668-A1 | TETRAMALEIMIDE LINKERS AND USE THEREOF | MCTS1, CA14, TTL | ALDH1A1 987/4885CA1 116/4885CA12 11/4885 |
| US-11666623-B2 | Tetramaleimide linkers and use thereof | MCTS1, CA14, TTL | ALDH1A1 987/4885CA1 116/4885CA12 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.