Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15371185 | 0.80 | CA2 (0.40) | CA2PRMT6HTTCYP3A4 | |
| SCHEMBL23879711 | 0.78 | PRMT6 (0.61) | CA2PRMT6GAAALDH1A1LMNA | |
| SCHEMBL15371157 | 0.74 | PLAU (0.53) | CA2PRMT6HTTALDH1A1ADRB2 | |
| SCHEMBL14350119 | 0.67 | KDM4E (0.55) | HTTGAAKDM4EALDH1A1LMNA | |
| SCHEMBL15961524 | 0.67 | CYP2A6 (0.67) | CA2KDM4EALDH1A1HPGDADRB2 | |
| SCHEMBL12657211 | 0.66 | — | — | |
| SCHEMBL10245713 | 0.65 | HTT (0.58) | HTTGAAKDM4EALDH1A1HPGD | |
| SCHEMBL99745 | 0.64 | — | — | |
| SCHEMBL23432959 | 0.64 | HRH3 (0.37) | CA2HTTGAAKDM4EALDH1A1 | |
| SCHEMBL10204766 | 0.64 | L3MBTL1 (0.46) | CA2GAAALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021080980-A1 | PYRIMIDINE AMIDE COMPOUNDS AND USE THEREOF | ALPHALA CO., LTD. (TW) | 2021-04-29 | — | — | WO | disclosed |