Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL446332 | 0.70 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL25425375 | 0.68 | — | — | |
| SCHEMBL11109665 | 0.67 | MAPT (0.34) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL497608 | 0.60 | — | — | |
| SCHEMBL5657603 | 0.59 | KDM4E (0.35) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL13185230 | 0.59 | MAPT (0.37) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL643612 | 0.59 | ALDH1A1 (0.34) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11286601 | 0.58 | — | — | |
| SCHEMBL3657117 | 0.58 | — | — | |
| SCHEMBL30497927 | 0.58 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2089425-B1 | ANTI-ANGIOGENIC COMPOUNDS | COVX TECHNOLOGIES IRELAND LTD (IE) | 2011-08-17 | — | — | EP | disclosed |