SCHEMBL446332

SCHEMBL446332

C1=CSC(c2cccs2)S1

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
MAPT P10636 4/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
KDM4E B2RXH2 3/20 0.37
HPGD P15428 3/20 0.37
ALOX15 P16050 2/20 0.37
ALOX12 P18054 1/20 0.37
TSHR P16473 1/20 0.36
HTT P42858 1/20 0.36
GAA P10253 3/20 0.35
POLB P06746 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C19 P33261 1/20 0.35
LMNA P02545 1/20 0.33
NOS2 P35228 1/20 0.33
TP53 P04637 1/20 0.33
FBP1 P09467 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25425375 0.72
SCHEMBL9414178 0.71 BCHE (0.41) ALDH1A1MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL2329915 0.70 ALDH1A1 (0.37) ALDH1A1MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL145927 0.70 MAPT (0.39) ALDH1A1MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL497608 0.69
SCHEMBL13185230 0.67 MAPT (0.37) ALDH1A1MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL5657603 0.67 KDM4E (0.35) ALDH1A1MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL643612 0.67 ALDH1A1 (0.34) ALDH1A1MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL3657117 0.67
Hydrochloric Acid SCHEMBL11286601 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118420693-A 6- (Isopropyl disulfide) -guanosine compound, and preparation method and application thereof 浙江大学金华研究院 2024-08-02 CN disclosed
CN-114605377-B Disulfide compound and synthesis thereof and application of disulfide compound in preparation of pseudomonas aeruginosa quorum sensing inhibitor 浙江工业大学 2023-09-05 CN disclosed
US-9631205-B2 Protein complex having activity catalyzing asymmetric oxidation reaction and process for producing the same SANYO FOODS CO., LTD. (JP) 2017-04-25 US disclosed
US-9556457-B2 Protein complex having activity catalyzing asymmetric oxidation reaction and process for producing the same SANYO FOODS CO., LTD. (JP) 2017-01-31 US disclosed
US-8852904-B2 Protein complex having activity catalyzing asymmetric oxidation reaction and process for producing the same SANYO FOODS CO., LTD. (JP) 2014-10-07 US disclosed
US-20130295642-A1 PROTEIN COMPLEX HAVING ACTIVITY CATALYZING ASYMMETRIC OXIDATION REACTION AND PROCESS FOR PRODUCING THE SAME SANYO FOODS CO., LTD. (JP) 2013-11-07 US disclosed
US-20130295626-A1 PROTEIN COMPLEX HAVING ACTIVITY CATALYZING ASYMMETRIC OXIDATION REACTION AND PROCESS FOR PRODUCING THE SAME SANYO FOODS CO., LTD. (JP) 2013-11-07 US disclosed
US-20120064588-A1 PROTEIN COMPLEX HAVING ACTIVITY CATALYZING ASYMMETRIC OXIDATION REACTION AND PROCESS FOR PRODUCING THE SAME SANYO FOODS CO., LTD. (JP) 2012-03-15 US disclosed
EP-0585999-A1 Functional heteroaromatics for NLO applications ENICHEM S.p.A. (IT) 1994-03-09 EP disclosed