Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K8 | P41279 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 16/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29656430 | 1.00 | MAP3K8 (0.39) | MAP3K8ARNR1H2NR1H3KDM4E | |
| SCHEMBL4961962 | 0.79 | ALDH1A1 (0.40) | MAP3K8ARNR1H2NR1H3ALDH1A1 | |
| SCHEMBL1124839 | 0.78 | NR1H2 (0.47) | ARNR1H2NR1H3 | |
| SCHEMBL19889984 | 0.74 | AR (0.38) | MAP3K8ARNR1H2NR1H3EGFR | |
| SCHEMBL18244728 | 0.73 | AR (0.46) | AR | |
| SCHEMBL30054555 | 0.73 | AR (0.46) | AR | |
| SCHEMBL21143432 | 0.72 | EGFR (0.44) | KDM4EEGFR | |
| SCHEMBL19889982 | 0.70 | KHK (0.36) | MAP3K8EGFR | |
| SCHEMBL29656689 | 0.69 | ALDH1A1 (0.36) | KDM4EALDH1A1 | |
| SCHEMBL23301651 | 0.69 | ALDH1A1 (0.36) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4643644-A2 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | Syngenta Crop Protection AG (CH) | 2025-11-05 | — | — | EP | disclosed |
| EP-4051673-B1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2025-09-24 | — | — | EP | disclosed |
| US-20230002359-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-01-05 | — | — | US | disclosed |
| US-20230002359-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-01-05 | — | — | US | disclosed |
| EP-4051673-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | Syngenta Crop Protection AG (CH) | 2022-09-07 | — | — | EP | disclosed |
| WO-2021083936-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-05-06 | — | — | WO | disclosed |
| WO-2021083936-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002359-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | DDT, ACHE, GSTO1 | MAP3K8 3593/4885AR 2034/4885NR1H2 2995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.