Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 5/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ATP4A | P20648 | 1/20 | 0.38 |
| ▸ | ATP4B | P51164 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8263596 | 0.82 | PARP1 (0.54) | PARP1DRD2DRD4DRD3ADRB2 | |
| SCHEMBL5788740 | 0.82 | PARP1 (0.54) | PARP1DRD2DRD4DRD3ADRB2 | |
| SCHEMBL22023670 | 0.81 | PARP1 (0.53) | PARP1DRD2DRD4DRD3ADRB2 | |
| SCHEMBL4191637 | 0.81 | PARP1 (0.53) | PARP1DRD2DRD4DRD3ADRB2 | |
| SCHEMBL8262961 | 0.78 | ADRB2 (0.55) | PARP1DRD2DRD4DRD3ADRB2 | |
| SCHEMBL16097301 | 0.78 | POLB (0.46) | POLB | |
| SCHEMBL6697342 | 0.77 | DRD2 (0.50) | PARP1DRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL3857628 | 0.76 | POLB (0.47) | PARP1POLB | |
| SCHEMBL12109684 | 0.76 | PARP1 (0.48) | PARP1DRD2DRD4DRD3ADRB2 | |
| SCHEMBL7981913 | 0.75 | DRD2 (0.49) | PARP1DRD2DRD4DRD3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011098829-A1 | NUCLEIC ACID COMPLEXES | PROCARTA BIOSYSTEMS LTD (GB) | 2011-08-18 | — | — | WO | disclosed |