Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.49 |
| ▸ | SERPINA6 | P08185 | 5/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.49 |
| ▸ | SHBG | P04278 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.49 |
| ▸ | PGR | P06401 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8907648 | 0.93 | NR3C1 (0.56) | NR3C1MAPK1ALDH1A1HSD17B10HIF1A | |
| SCHEMBL94105 | 0.87 | HIF1A (0.63) | NR3C1MAPK1ALDH1A1HSD17B10HIF1A | |
| SCHEMBL20575301 | 0.86 | NR3C1 (0.56) | NR3C1MAPK1ALDH1A1HSD17B10HIF1A | |
| SCHEMBL7766720 | 0.85 | HIF1A (0.55) | NR3C1MAPK1ALDH1A1HSD17B10HIF1A | |
| SCHEMBL2981243 | 0.85 | HSD17B10 (0.60) | NR3C1MAPK1ALDH1A1HSD17B10HIF1A | |
| SCHEMBL28318620 | 0.84 | HIF1A (0.60) | NR3C1MAPK1ALDH1A1HSD17B10HIF1A | |
| SCHEMBL8061818 | 0.83 | HIF1A (0.59) | NR3C1MAPK1ALDH1A1HSD17B10HIF1A | |
| SCHEMBL6370137 | 0.83 | HIF1A (0.59) | NR3C1MAPK1ALDH1A1HSD17B10HIF1A | |
| Butyric Acid SCHEMBL28142317 | 0.82 | HIF1A (0.57) | NR3C1MAPK1ALDH1A1HSD17B10HIF1A | |
| SCHEMBL24461 | 0.81 | SERPINA6 (0.57) | NR3C1MAPK1ALDH1A1HSD17B10HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2356453-A2 | METABOLIC SYNDROME AND HPA AXIS BIOMARKERS FOR MAJOR DEPRESSIVE DISORDER | Ridge Diagnostics, Inc. (US) | 2011-08-17 | — | — | EP | disclosed |
| WO-2010059709-A2 | METABOLIC SYNDROME AND HPA AXIS BIOMARKERS FOR MAJOR DEPRESSIVE DISORDER | RIDGE DIAGNOSTICS, INC. (US) | 2010-05-27 | — | — | WO | disclosed |
| EP-1668345-A1 | IMMUNOASSAY | The Horticulture and Food Research Institute of New Zealand Limited (NZ) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005026702-A1 | IMMUNOASSAY | THE HORTICULTURE AND FOOD RESEARCH INSTITUTE OF NEW ZEALAND LIMITED (NZ) | 2005-03-24 | — | — | WO | disclosed |