Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 10/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.57 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.57 |
| ▸ | PGR | P06401 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.57 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | SHBG | P04278 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.49 |
| ▸ | IL6 | P05231 | 1/20 | 0.49 |
| ▸ | GLUL | P15104 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL94105 | 0.94 | HIF1A (0.63) | HIF1AHSD17B10NR3C1CYP2C19PGR | |
| SCHEMBL28318620 | 0.92 | HIF1A (0.60) | HIF1AHSD17B10NR3C1CYP2C19PGR | |
| SCHEMBL6370137 | 0.91 | HIF1A (0.59) | HIF1AHSD17B10NR3C1CYP2C19PGR | |
| SCHEMBL8061818 | 0.91 | HIF1A (0.59) | HIF1AHSD17B10NR3C1CYP2C19PGR | |
| SCHEMBL7973569 | 0.90 | NR3C2 (0.63) | HIF1AHSD17B10NR3C1CYP2C19PGR | |
| SCHEMBL7766720 | 0.86 | HIF1A (0.55) | HIF1AHSD17B10NR3C1CYP2C19PGR | |
| SCHEMBL24461 | 0.84 | SERPINA6 (0.57) | HIF1AHSD17B10NR3C1CYP2C19PGR | |
| SCHEMBL2981243 | 0.83 | HSD17B10 (0.60) | HIF1AHSD17B10NR3C1CYP2C19PGR | |
| SCHEMBL2330386 | 0.82 | NR3C1 (0.59) | HIF1AHSD17B10NR3C1CYP2C19PGR | |
| Butyric Acid SCHEMBL28140488 | 0.82 | HIF1A (0.59) | HIF1AHSD17B10NR3C1CYP2C19PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103476412-B | Aclidinium for improving sleep quality in patients with respiratory diseases | 阿尔米雷尔有限公司 | 2017-07-14 | — | — | CN | disclosed |