⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23317400 | 0.86 | GPR119 (0.34) | — | |
| SCHEMBL23305171 | 0.85 | — | — | |
| SCHEMBL23304715 | 0.85 | IRAK4 (0.32) | — | |
| SCHEMBL30200940 | 0.84 | CCNC (0.30) | — | |
| SCHEMBL23304778 | 0.84 | CCNC (0.30) | — | |
| SCHEMBL23305557 | 0.83 | ACACB (0.34) | — | |
| SCHEMBL23304876 | 0.83 | HPGDS (0.32) | — | |
| SCHEMBL23304822 | 0.82 | IRAK4 (0.30) | — | |
| SCHEMBL23304675 | 0.82 | HCAR3 (0.36) | — | |
| SCHEMBL23304726 | 0.81 | MAPT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230060003-A1 | SPIROCYCLIC O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. | 2023-02-23 | — | — | US | disclosed |
| WO-2021086966-A1 | SPIROCYCLIC O-GLYCOPROTEIN-2-ACETAMIDO-2-DEOXY-3-D-GLUCOPYRANOSIDASE INHIBITORS | BIOGEN MA INC. (US) | 2021-05-06 | — | — | WO | disclosed |