Sugi Predict

Sugi Predict / Compounds / SCHEMBL2330737

SCHEMBL2330737

SCHEMBL2330737

CCCCCCN(CCCCCC)C([O])=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA12 O43570 3/20 0.52
▸ CA1 P00915 3/20 0.52
▸ CA9 Q16790 3/20 0.52
▸ CA2 P00918 1/20 0.52
▸ MGLL Q99685 1/20 0.47
▸ DNM1 Q05193 3/20 0.46
▸ ZDHHC20 Q5W0Z9 2/20 0.46
▸ ZDHHC2 Q9UIJ5 1/20 0.46
▸ MMP1 P03956 1/20 0.45
▸ MMP2 P08253 1/20 0.45
▸ MMP3 P08254 1/20 0.45
▸ MMP8 P22894 1/20 0.45
▸ CES2 O00748 3/20 0.44
▸ CES1 P23141 3/20 0.44
▸ PPARG P37231 5/20 0.42
▸ PPARD Q03181 5/20 0.42
▸ PPARA Q07869 5/20 0.42
▸ HDAC11 Q96DB2 4/20 0.42
▸ TSHR P16473 3/20 0.42
▸ GPR84 Q9NQS5 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7652811 1.00 CA12 (0.52) CA12CA1CA9CA2MGLL
SCHEMBL55097 1.00 CA12 (0.52) CA12CA1CA9CA2MGLL
SCHEMBL1829047 0.97 CA12 (0.50) CA12CA1CA9CA2MGLL
SCHEMBL2333118 0.90 CA12 (0.58) CA12CA1CA9CA2ZDHHC20
SCHEMBL29210381 0.85 CA12 (0.54) CA12CA1CA9CA2MMP1
SCHEMBL25277341 0.82 CA12 (0.54) CA12CA1CA9CA2MGLL
SCHEMBL25278271 0.82 CA12 (0.54) CA12CA1CA9CA2MGLL
SCHEMBL25220731 0.82 CA12 (0.54) CA12CA1CA9CA2MGLL
SCHEMBL13622903 0.82 CA12 (0.54) CA12CA1CA9CA2MGLL
SCHEMBL25227890 0.82 CA12 (0.54) CA12CA1CA9CA2MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11160785-B2 Methods and compositions for improving cognitive function AGENEBIO INC. (US) 2021-11-02 — — US disclosed
US-20180015109-A1 METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION THE JOHNS HOPKINS UNIVERSITY 2018-01-18 — — US disclosed
US-20160271108-A1 METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION AGENEBIO, INC. 2016-09-22 — — US disclosed
EP-2533645-B1 METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION UNIV JOHNS HOPKINS (US) 2016-07-27 — — EP disclosed
EP-2968220-A1 METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION Agenebio, Inc. (US) 2016-01-20 — — EP disclosed
WO-2014144801-A1 METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION AGENEBIO INC. (US) 2014-09-18 — — WO disclosed
EP-2533645-A1 METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION The Johns Hopkins University (US) 2012-12-19 — — EP disclosed
US-20110212928-A1 METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION THE JOHNS HOPKINS UNIVERSITY (US) 2011-09-01 — — US disclosed
WO-2011100373-A1 METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION THE JOHNS HOPKINS UNIVERSITY (US) 2011-08-18 — — WO disclosed
US-20090137629-A1 Sigma receptor binding agent containing indanone derivative IIMURA YOICHI 2009-05-28 — — US disclosed
EP-0560613-A1 Antimicrobial carbapenem derivatives, their preparation and their therapeutic use SANKYO COMPANY LIMITED (JP) 1993-09-15 — — EP disclosed
EP-0339562-B1 BENZOPYRAN COMPOUND AND ITS PHARMACEUTICAL USE YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1993-09-15 — — EP disclosed
EP-0505565-A1 QUINOLINE DERIVATIVES, THEIR PRODUCTION AND USE. TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1992-09-30 — — EP disclosed
US-5143936-A Benzopyran compound and its pharmaceutical use YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1992-09-01 — — US disclosed
EP-0470514-A1 Carbostyril derivatives and pharmaceutical composition containing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-02-12 — — EP disclosed
EP-0450097-A1 BENZOHETEROCYCLIC COMPOUNDS. OTSUKA PHARMA CO LTD (JP) 1991-10-09 — — EP disclosed
WO-1991009017-A1 QUINOLINE DERIVATIVES, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-06-27 — — WO disclosed
US-5021432-A Hypotensive agents YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1991-06-04 — — US disclosed
WO-1991005549-A1 BENZOHETEROCYCLIC COMPOUNDS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-05-02 — — WO disclosed
EP-0339562-A1 Benzopyran compound and its pharmaceutical use YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1989-11-02 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160271108-A1 METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION BACE2, BACE1, GRIN2A CA12 483/4885CA1 828/4885CA9 3429/4885
US-11160785-B2 Methods and compositions for improving cognitive function BACE2, BACE1, GRIN2A CA12 483/4885CA1 828/4885CA9 3429/4885
US-20180015109-A1 METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION BACE1, BACE2, ACHE CA12 825/4885CA1 350/4885CA9 3386/4885
US-20090137629-A1 Sigma receptor binding agent containing indanone derivative SIGMAR1, TMEM97, OPRK1 CA12 4421/4885CA1 3368/4885CA9 4833/4885
US-20110212928-A1 METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION BACE1, BACE2, ACHE CA12 825/4885CA1 350/4885CA9 3386/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.