SCHEMBL23310068

SCHEMBL23310068

Clc1ccc(-c2ccc3c4c5ccccc5oc4n(-c4ccccc4)c3c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.40
TNKS O95271 1/20 0.40
MAT2A P31153 5/20 0.36
RET P07949 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
MAPK8 P45983 1/20 0.35
MAPK9 P45984 1/20 0.35
TRPA1 O75762 1/20 0.34
TRPM8 Q7Z2W7 1/20 0.34
PRMT5 O14744 1/20 0.34
CYP1A2 P05177 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23310227 0.90 L3MBTL1 (0.38) AHRTNKSMAT2AMAPK8MAPK9
SCHEMBL23310149 0.90 TNKS (0.40) AHRTNKSRETCA1CA2
SCHEMBL24639634 0.88 KDM4E (0.45) ALDH1A1RXFP1MEN1LMNAKMT2A
SCHEMBL24639114 0.88 KDM4E (0.45) ALDH1A1RXFP1MEN1LMNAKMT2A
SCHEMBL23310133 0.88 L3MBTL1 (0.38) AHRTNKSCYP1A2ALDH1A1MAPT
SCHEMBL24639672 0.88 KDM4E (0.45) ALDH1A1RXFP1MEN1LMNAKMT2A
SCHEMBL24639069 0.85 PLA2G2A (0.37) TNKSCA1CA2ALDH1A1HPGD
SCHEMBL24639680 0.85 PLA2G2A (0.37) TNKSCA1CA2ALDH1A1HPGD
SCHEMBL16276643 0.85 L3MBTL1 (0.38) CYP1A2ALDH1A1MAPTNPSR1RXFP1
SCHEMBL24639651 0.84 L3MBTL1 (0.44) ALDH1A1MAPTRXFP1MEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210126198-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MONOAMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210126198-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND MONOAMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SLC18A1, SLC18A2, SLC18A3 AHR 525/4885TNKS 3662/4885MAT2A 1261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.