Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2331221 | 1.00 | TSHR (0.47) | TSHRALDH1A1KDM4ELMNACYP1A2 | |
| SCHEMBL2331227 | 1.00 | TSHR (0.47) | TSHRALDH1A1KDM4ELMNACYP1A2 | |
| SCHEMBL22303088 | 0.88 | TDP1 (0.50) | TSHRALDH1A1KDM4ELMNACYP1A2 | |
| SCHEMBL1880827 | 0.86 | TSHR (0.47) | TSHRALDH1A1KDM4ELMNACYP1A2 | |
| SCHEMBL2331029 | 0.83 | SMN1; SMN2 (0.51) | TSHRALDH1A1KDM4ECYP3A4GAA | |
| SCHEMBL3959577 | 0.83 | SMN1; SMN2 (0.51) | TSHRALDH1A1KDM4ECYP3A4GAA | |
| SCHEMBL28433726 | 0.83 | TP53 (0.46) | TSHRALDH1A1KDM4ELMNACYP1A2 | |
| Methyl Alcohol SCHEMBL8740643 | 0.81 | SMN1; SMN2 (0.50) | TSHRALDH1A1KDM4ECYP3A4GAA | |
| SCHEMBL14868118 | 0.79 | TSHR (0.56) | TSHRALDH1A1KDM4ELMNACYP3A4 | |
| SCHEMBL14868116 | 0.79 | TSHR (0.56) | TSHRALDH1A1KDM4ELMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534161-A1 | ENANTIOMERICALLY ENRICHED AMINODIPHOSPHINES AS LIGANDS FOR THE PREPARATION OF CATALYSTS FOR ASYMMETRIC SYNTHESIS | Enantia, S.L. (ES) | 2012-12-19 | — | — | EP | disclosed |
| US-20120309997-A1 | Enantiomerically Enriched Aminodiphosphines as Ligands for the Preparation of Catalysts for Asymmetric Synthesis | ENANTIA, S.L. (ES) | 2012-12-06 | — | — | US | disclosed |
| WO-2011098160-A1 | ENANTIOMERICALLY ENRICHED AMINODIPHOSPHINES AS LIGANDS FOR THE PREPARATION OF CATALYSTS FOR ASYMMETRIC SYNTHESIS | ENANTIA, S.L. (ES) | 2011-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309997-A1 | Enantiomerically Enriched Aminodiphosphines as Ligands for the Preparation of Catalysts for Asymmetric Synthesis | PHOSPHO1, AASDHPPT, AGPS | TSHR 4609/4885ALDH1A1 3462/4885KDM4E 1475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.