Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3959577 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2TDP1ALDH1A1KDM4EKMT2A | |
| Methyl Alcohol SCHEMBL8740643 | 0.98 | SMN1; SMN2 (0.50) | SMN1; SMN2TDP1ALDH1A1KDM4EKMT2A | |
| SCHEMBL2331227 | 0.83 | TSHR (0.47) | ALDH1A1KDM4EKMT2AMAPTL3MBTL1 | |
| SCHEMBL2331231 | 0.83 | TSHR (0.47) | ALDH1A1KDM4EKMT2AMAPTL3MBTL1 | |
| SCHEMBL2331221 | 0.83 | TSHR (0.47) | ALDH1A1KDM4EKMT2AMAPTL3MBTL1 | |
| SCHEMBL6142291 | 0.81 | CES2 (0.49) | SMN1; SMN2TDP1ALDH1A1KDM4EKMT2A | |
| SCHEMBL8654881 | 0.80 | CA1 (0.52) | SMN1; SMN2ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL8655472 | 0.77 | LCK (0.48) | SMN1; SMN2TDP1KMT2AMAPTNPC1 | |
| SCHEMBL15347751 | 0.75 | ALDH1A1 (0.42) | SMN1; SMN2TDP1ALDH1A1KDM4EKMT2A | |
| SCHEMBL863064 | 0.74 | ALDH1A1 (0.63) | SMN1; SMN2TDP1ALDH1A1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534161-A1 | ENANTIOMERICALLY ENRICHED AMINODIPHOSPHINES AS LIGANDS FOR THE PREPARATION OF CATALYSTS FOR ASYMMETRIC SYNTHESIS | Enantia, S.L. (ES) | 2012-12-19 | — | — | EP | disclosed |
| US-20120309997-A1 | Enantiomerically Enriched Aminodiphosphines as Ligands for the Preparation of Catalysts for Asymmetric Synthesis | ENANTIA, S.L. (ES) | 2012-12-06 | — | — | US | disclosed |
| WO-2011098160-A1 | ENANTIOMERICALLY ENRICHED AMINODIPHOSPHINES AS LIGANDS FOR THE PREPARATION OF CATALYSTS FOR ASYMMETRIC SYNTHESIS | ENANTIA, S.L. (ES) | 2011-08-18 | — | — | WO | disclosed |
| WO-2009030626-A1 | NEW PHOSPHINE-PHOSPHITE LIGANDS | INSTITUT CATALÀ D'INVESTIGACIÓ QUÍMICA (ICIQ) (ES) | 2009-03-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309997-A1 | Enantiomerically Enriched Aminodiphosphines as Ligands for the Preparation of Catalysts for Asymmetric Synthesis | PHOSPHO1, AASDHPPT, AGPS | SMN1; SMN2 4541/4885TDP1 3180/4885ALDH1A1 3462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.