Methyl Alcohol

Methyl Alcohol

SCHEMBL8740643

CC(=O)NC(C(=O)O)=C(C)c1ccccc1.CO

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
ALDH1A1 P00352 3/20 0.44
KDM4E B2RXH2 3/20 0.44
KMT2A Q03164 3/20 0.44
MAPT P10636 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
MEN1 O00255 2/20 0.44
NPC1 O15118 1/20 0.44
GLA P06280 1/20 0.44
RAB9A P51151 1/20 0.44
CYP19A1 P11511 3/20 0.44
GAA P10253 1/20 0.42
CES1 P23141 2/20 0.42
CES2 O00748 1/20 0.42
EPHX1 P07099 1/20 0.42
TSHR P16473 2/20 0.41
NAPRT Q6XQN6 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CACNA1B Q00975 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2331029 0.98 SMN1; SMN2 (0.51) SMN1; SMN2TDP1ALDH1A1KDM4EKMT2A
SCHEMBL3959577 0.98 SMN1; SMN2 (0.51) SMN1; SMN2TDP1ALDH1A1KDM4EKMT2A
SCHEMBL2331227 0.81 TSHR (0.47) ALDH1A1KDM4EKMT2AMAPTL3MBTL1
SCHEMBL2331231 0.81 TSHR (0.47) ALDH1A1KDM4EKMT2AMAPTL3MBTL1
SCHEMBL2331221 0.81 TSHR (0.47) ALDH1A1KDM4EKMT2AMAPTL3MBTL1
SCHEMBL6142291 0.80 CES2 (0.49) SMN1; SMN2TDP1ALDH1A1KDM4EKMT2A
SCHEMBL8654881 0.79 CA1 (0.52) SMN1; SMN2ALDH1A1KDM4EMAPTNPC1
SCHEMBL8655472 0.75 LCK (0.48) SMN1; SMN2TDP1KMT2AMAPTNPC1
SCHEMBL15347751 0.74 ALDH1A1 (0.42) SMN1; SMN2TDP1ALDH1A1KDM4EKMT2A
SCHEMBL863064 0.73 ALDH1A1 (0.63) SMN1; SMN2TDP1ALDH1A1KDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0746410-A4 WATER-SOLUBLE CHIRAL SULFONATED BINAP CATALYST FOR ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS CALIFORNIA INST OF TECHN (US) 1997-04-09 EP disclosed
EP-0746410-A1 WATER-SOLUBLE CHIRAL SULFONATED BINAP CATALYST FOR ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1996-12-11 EP disclosed
WO-1995022405-A1 WATER-SOLUBLE CHIRAL SULFONATED BINAP CATALYST FOR ASYMMETRIC SYNTHESIS OF OPTICALLY ACTIVE COMPOUNDS CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 1995-08-24 WO disclosed