Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1443658 | 0.85 | SHBG (0.46) | SHBGCYP1A2 | |
| SCHEMBL18600333 | 0.83 | — | — | |
| SCHEMBL31458641 | 0.81 | GNAO1 (0.36) | — | |
| SCHEMBL22803237 | 0.77 | — | — | |
| SCHEMBL19257785 | 0.77 | MAPT (0.43) | MAPTCYP1A2 | |
| SCHEMBL910914 | 0.76 | — | — | |
| SCHEMBL18862407 | 0.76 | SHBG (0.43) | SHBG | |
| SCHEMBL9057669 | 0.76 | TLR4 (0.35) | SHBGCYP1A2 | |
| SCHEMBL19988266 | 0.76 | — | — | |
| SCHEMBL23312962 | 0.75 | METAP1 (0.33) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008104756-A1 | UREA DERIVATIVES AND THEIR THERAPEUTIC USE | SERENTIS LIMITED (GB) | 2008-09-04 | — | — | WO | disclosed |