Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30171993 | 0.77 | OPRM1 (0.31) | OPRM1OPRL1 | |
| SCHEMBL595778 | 0.76 | CYP2C19 (0.37) | — | |
| SCHEMBL27628685 | 0.76 | MEN1 (0.39) | — | |
| SCHEMBL23042634 | 0.75 | SLC6A2 (0.32) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2331297 | 0.75 | SLC6A3 (0.41) | SLC6A2SLC6A4OPRM1SLC6A3 | |
| Hydrochloric Acid SCHEMBL8611493 | 0.73 | SLC6A4 (0.39) | SLC6A2SLC6A4OPRM1SLC6A3 | |
| SCHEMBL5049749 | 0.72 | SLC6A4 (0.35) | SLC6A4OPRM1OPRL1SLC6A3 | |
| SCHEMBL1988629 | 0.72 | SLC6A4 (0.35) | SLC6A4OPRM1OPRL1SLC6A3 | |
| SCHEMBL9654521 | 0.72 | RYR2 (0.33) | OPRM1OPRL1 | |
| SCHEMBL322047 | 0.72 | SLC6A4 (0.35) | SLC6A4OPRM1OPRL1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028816-A1 | SUBSTITUTED 5-AMINO-1-PENTENE-3-OL DERIVATIVES | BUSCHMANN, HELMUT | 2002-04-11 | — | — | WO | disclosed |