SCHEMBL23313384

SCHEMBL23313384

c1ccc(-c2ccc(Nc3cccc4c3sc3ccccc34)cc2-c2cccc3sc4ccccc4c23)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP14 Q460N5 1/20 0.39
ALOX5 P09917 1/20 0.38
LIMK1 P53667 2/20 0.36
PTGIR P43119 1/20 0.35
TNKS O95271 1/20 0.33
TNKS2 Q9H2K2 1/20 0.33
EGFR P00533 1/20 0.33
F9 P00740 1/20 0.33
BRDT Q58F21 1/20 0.32
GPR3 P46089 1/20 0.32
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
GLA P06280 1/20 0.31
GAA P10253 1/20 0.31
RECQL P46063 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
SLC9A1 P19634 1/20 0.31
TDO2 P48775 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23313711 0.95 PARP14 (0.39) PARP14ALOX5LIMK1PTGIRTNKS
SCHEMBL23313533 0.91 PARP14 (0.47) PARP14ALOX5LIMK1PTGIRTNKS
SCHEMBL26634584 0.90 LIMK1 (0.41) PARP14ALOX5LIMK1PTGIRTNKS
SCHEMBL26634575 0.82 PTGIR (0.38) PARP14ALOX5LIMK1PTGIREGFR
SCHEMBL23314088 0.82 BRDT (0.36) ALOX5F9BRDTMAPT
SCHEMBL23313998 0.82 ALOX5 (0.40) PARP14ALOX5TNKSTNKS2EGFR
SCHEMBL23314079 0.81 ALOX5 (0.44) PARP14ALOX5LIMK1PTGIRTNKS
SCHEMBL25636210 0.79 MEN1 (0.42) PARP14ALOX5LIMK1F9GPR3
SCHEMBL24944486 0.79 PARP14 (0.41) PARP14ALOX5LIMK1TNKSTNKS2
SCHEMBL18311793 0.79 PTGIR (0.51) PARP14ALOX5PTGIREGFRGPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210126197-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND AMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210126197-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND AMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE PIEZO1, L1CAM, AOC1 PARP14 1894/4885ALOX5 1383/4885LIMK1 108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.