SCHEMBL2331340

SCHEMBL2331340

Cc1ccc2c(c1)C(=O)N(Cc1cccc(CN3Cc4ccc(C)cc4C3=O)c1)C2

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
POLB P06746 1/20 0.48
HDAC1 Q13547 3/20 0.46
HDAC4 P56524 2/20 0.46
HDAC6 Q9UBN7 2/20 0.46
ACHE P22303 2/20 0.44
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
CYP3A4 P08684 1/20 0.43
RECQL P46063 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
DHPS P49366 1/20 0.42
MAPK1 P28482 3/20 0.41
HDAC7 Q8WUI4 1/20 0.41
MAPK3 P27361 1/20 0.41
NR3C1 P04150 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15120603 0.91 HDAC1 (0.55) MEN1KMT2APOLBHDAC1HDAC4
SCHEMBL12363333 0.89 KMT2A (0.47) MEN1KMT2AHDAC1HDAC4HDAC6
SCHEMBL12204890 0.87 HDAC4 (0.41) MEN1KMT2APOLBHDAC1HDAC4
SCHEMBL12418589 0.84 MEN1 (0.55) MEN1KMT2APOLBHDAC1HDAC4
SCHEMBL31667370 0.83 MEN1 (0.48) MEN1KMT2AHDAC1HDAC4HDAC6
SCHEMBL2192290 0.81 HDAC1 (0.56) MEN1KMT2AHDAC1HDAC4HDAC6
SCHEMBL12204910 0.81 MEN1 (0.49) MEN1KMT2APOLBHDAC1HDAC4
SCHEMBL10274610 0.80 ACACB (0.44) MEN1KMT2AHDAC1HDAC4HDAC6
SCHEMBL12581806 0.79 MEN1 (0.50) MEN1KMT2APOLBHDAC1HDAC4
SCHEMBL12446493 0.79 HDAC1 (0.52) MEN1KMT2APOLBHDAC1HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11739059-B2 Oxygen scavenging molecules, articles containing same, and methods of their use PLASTIPAK PACKAGING, INC. (US) 2023-08-29 US disclosed
US-11739059-B2 Oxygen scavenging molecules, articles containing same, and methods of their use PLASTIPAK PACKAGING, INC. (US) 2023-08-29 US disclosed
US-11739059-B2 Oxygen scavenging molecules, articles containing same, and methods of their use PLASTIPAK PACKAGING, INC. (US) 2023-08-29 US disclosed
US-11649339-B2 Oxygen scavenging compositions, articles containing same, and methods of their use PLASTIPAK PACKAGING, INC. (US) 2023-05-16 US disclosed
US-11649339-B2 Oxygen scavenging compositions, articles containing same, and methods of their use PLASTIPAK PACKAGING, INC. (US) 2023-05-16 US disclosed
US-11345534-B2 Oxygen scavenging compositions, articles containing same, and methods of their use PLASTIPAK PACKAGING, INC. (US) 2022-05-31 US disclosed
US-11338983-B2 Oxygen scavenging compositions, articles containing same, and methods of their use PLASTIPAK PACKAGING, INC. (US) 2022-05-24 US disclosed
US-20210403423-A1 OXYGEN SCAVENGING MOLECULES, ARTICLES CONTAINING SAME, AND METHODS OF THEIR USE WELLS FARGO BANK, N.A., AS ADMINISTRATIVE AGENT 2021-12-30 US disclosed
US-20210403423-A1 OXYGEN SCAVENGING MOLECULES, ARTICLES CONTAINING SAME, AND METHODS OF THEIR USE WELLS FARGO BANK, N.A., AS ADMINISTRATIVE AGENT 2021-12-30 US disclosed
US-10906870-B2 Oxygen scavenging molecules, articles containing same, and methods of their use PLASTIPAK PACKAGING, INC. (US) 2021-02-02 US disclosed
US-20110251395-A1 OXYGEN SCAVENGING MOLECULES, ARTICLES CONTAINING SAME, AND METHODS OF THEIR USE WELLS FARGO BANK, N.A., AS ADMINISTRATIVE AGENT 2011-10-13 US disclosed
US-20110251395-A1 OXYGEN SCAVENGING MOLECULES, ARTICLES CONTAINING SAME, AND METHODS OF THEIR USE WELLS FARGO BANK, N.A., AS ADMINISTRATIVE AGENT 2011-10-13 US disclosed
US-7994245-B2 Oxygen scavenging molecules, articles containing same, and methods of their use CONSTAR INTERNATIONAL L.L.C. (US) 2011-08-09 US disclosed
US-7994245-B2 Oxygen scavenging molecules, articles containing same, and methods of their use CONSTAR INTERNATIONAL L.L.C. (US) 2011-08-09 US disclosed
US-7994245-B2 Oxygen scavenging molecules, articles containing same, and methods of their use CONSTAR INTERNATIONAL L.L.C. (US) 2011-08-09 US disclosed
WO-2008141185-A9 OXYGEN SCAVENGING MOLECULES, ARTICLES CONTAINING SAME, AND METHODS OF THEIR USE CONSTAR INTERNATIONAL, INC. (US) 2009-09-24 WO disclosed
WO-2008141185-A1 OXYGEN SCAVENGING MOLECULES, ARTICLES CONTAINING SAME, AND METHODS OF THEIR USE CONSTAR INTERNATIONAL, INC. (US) 2008-11-20 WO disclosed
US-20080277622-A1 Oxygen Scavenging Molecules, Articles Containing Same, And Methods Of Their Use WELLS FARGO BANK, N.A., AS ADMINISTRATIVE AGENT 2008-11-13 US disclosed
US-20080277622-A1 Oxygen Scavenging Molecules, Articles Containing Same, And Methods Of Their Use WELLS FARGO BANK, N.A., AS ADMINISTRATIVE AGENT 2008-11-13 US disclosed
US-20080277622-A1 Oxygen Scavenging Molecules, Articles Containing Same, And Methods Of Their Use WELLS FARGO BANK, N.A., AS ADMINISTRATIVE AGENT 2008-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080277622-A1 Oxygen Scavenging Molecules, Articles Containing Same, And Methods Of Their Use SCO2, SQOR, DUOX2 MEN1 3526/4885KMT2A 3643/4885POLB 904/4885
US-20110251395-A1 OXYGEN SCAVENGING MOLECULES, ARTICLES CONTAINING SAME, AND METHODS OF THEIR USE SCO2, SOD1, SQOR MEN1 3418/4885KMT2A 3848/4885POLB 826/4885
US-10906870-B2 Oxygen scavenging molecules, articles containing same, and methods of their use SQOR, SCO2, SOD1 MEN1 3145/4885KMT2A 3472/4885POLB 972/4885
US-11739059-B2 Oxygen scavenging molecules, articles containing same, and methods of their use SQOR, SCO2, DUOX2 MEN1 3146/4885KMT2A 3498/4885POLB 961/4885
US-20210403423-A1 OXYGEN SCAVENGING MOLECULES, ARTICLES CONTAINING SAME, AND METHODS OF THEIR USE SQOR, SCO2, DUOX2 MEN1 3146/4885KMT2A 3498/4885POLB 961/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.