SCHEMBL2331358

SCHEMBL2331358

Nc1ccc2ccccc2[n+]1C(I)CCCCCCCCC(I)[n+]1c(N)ccc2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BCHE P06276 14/20 0.39
ACHE P22303 14/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14740356 0.82 KDM4E (0.39) BCHEACHE
SCHEMBL2332858 0.71 BCHE (0.46) BCHEACHE
SCHEMBL2335924 0.67 PRKCA (0.55) ACHE
Iodide SCHEMBL2331356 0.66 BCHE (0.52) BCHEACHE
SCHEMBL2336825 0.65 ACHE (0.37) BCHEACHE
SCHEMBL14738733 0.64 CHKA (0.40) ACHE
SCHEMBL14739219 0.64 CHKA (0.40) ACHE
SCHEMBL2329328 0.64 CHKA (0.40) ACHE
SCHEMBL14740376 0.61 CHKA (0.41) ACHE
SCHEMBL13979479 0.61 ACHE (0.46) BCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150196652-A1 NUCLEIC ACID COMPLEXES PROCARTA BIOSYSTEMS LTD (GB) 2015-07-16 US disclosed
US-9024005-B2 Nucleic acid complexes PROCARTA BIOSYSTEMS LTD (GB) 2015-05-05 US disclosed
US-20140274800-A1 TRANSCRIPTION FACTOR DECOYS FOR THE TREATMENT AND PREVENTION OF INFECTIONS CAUSED BY BACTERIA INCLUDING CLOSTRIDIUM DIFFICILE PROCARTA BIOSYSTEMS LTD. (GB) 2014-09-18 US disclosed
US-20130252881-A1 Transcription Factor Decoys PROCARTA BIOSYSTEMS LTD. (GB) 2013-09-26 US disclosed
US-20130059775-A1 Nucleic Acid Complexes PROCARTA BIOSYSTEMS LTD (GB) 2013-03-07 US disclosed
EP-2533815-A1 NUCLEIC ACID COMPLEXES Procarta Biosystems Ltd (GB) 2012-12-19 EP disclosed
WO-2011098829-A1 NUCLEIC ACID COMPLEXES PROCARTA BIOSYSTEMS LTD (GB) 2011-08-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150196652-A1 NUCLEIC ACID COMPLEXES ZFR, SUB1, RELA BCHE 4569/4885ACHE 4834/4885
US-20130059775-A1 Nucleic Acid Complexes ZFR, SUB1, RELA BCHE 4569/4885ACHE 4834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.