SCHEMBL23314036

SCHEMBL23314036

c1ccc(-c2cc(Nc3cccc4c3oc3ccccc34)ccc2-c2cccc3c2sc2ccccc23)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP14 Q460N5 1/20 0.40
ALOX5 P09917 3/20 0.37
PRKDC P78527 7/20 0.36
PIK3CD O00329 2/20 0.36
PIK3CB P42338 2/20 0.36
BRD4 O60885 1/20 0.36
PIK3CA P42336 1/20 0.36
MTOR P42345 1/20 0.36
PIK3CG P48736 1/20 0.36
KCNH2 Q12809 1/20 0.36
BRDT Q58F21 1/20 0.36
PTGES2 Q9H7Z7 1/20 0.35
GGPS1 O95749 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
ESR2 Q92731 1/20 0.31
TNKS O95271 1/20 0.31
TNKS2 Q9H2K2 1/20 0.31
F9 P00740 1/20 0.31
AKR1C3 P42330 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23313544 0.96 PARP14 (0.40) PARP14ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL23313998 0.88 ALOX5 (0.40) PARP14ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL18201527 0.87 ALOX5 (0.45) PARP14ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL23313701 0.86 ALOX5 (0.48) ALOX5PRKDCPIK3CDPIK3CBPTGES2
SCHEMBL31146678 0.84 ALOX5 (0.42) ALOX5PTGES2GGPS1ALDH1A1MAPT
SCHEMBL23314088 0.84 BRDT (0.36) ALOX5BRDTPTGES2GGPS1ALDH1A1
SCHEMBL23313947 0.82 ALOX5 (0.39) PARP14ALOX5PRKDCPIK3CDPIK3CB
SCHEMBL23313727 0.82 ALOX5 (0.43) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL23314006 0.82 PRKDC (0.39) PARP14ALOX5PRKDCALDH1A1MAPT
SCHEMBL23313533 0.81 PARP14 (0.47) PARP14ALOX5PRKDCPIK3CDPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210126197-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND AMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2021-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210126197-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND AMINE COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE PIEZO1, L1CAM, AOC1 PARP14 1894/4885ALOX5 1383/4885PRKDC 3926/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.