SCHEMBL23314261

SCHEMBL23314261

Nc1ccc(COCc2cccc(N)c2)cc1

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.62
MAOB P27338 11/20 0.50
MAOA P21397 5/20 0.48
TSHR P16473 1/20 0.48
APP P05067 1/20 0.46
GAA P10253 1/20 0.46
MAPT P10636 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
LOXL2 Q9Y4K0 1/20 0.43
CYP3A4 P08684 1/20 0.42
CASP1 P29466 1/20 0.42
RECQL P46063 1/20 0.42
MRGPRX4 Q96LA9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL366865 0.92 MAOB (0.56) CYP19A1MAOBMAOATSHRAPP
SCHEMBL31568426 0.90 TSHR (0.62) CYP19A1MAOBMAOATSHRAPP
SCHEMBL22469788 0.90 TSHR (0.62) CYP19A1MAOBMAOATSHRAPP
SCHEMBL18217412 0.83 MAOB (0.52) CYP19A1MAOBMAOATSHRAPP
SCHEMBL14378833 0.83 TSHR (0.71) MAOBMAOATSHRGAAMAPT
SCHEMBL234606 0.82 ALDH1A1 (0.55) MAOBMAOATSHRAPPGAA
SCHEMBL9804198 0.80 MAOB (0.48) CYP19A1MAOBMAOATSHRAPP
SCHEMBL8011823 0.80 CYP3A4 (0.50) CYP19A1MAOBMAOATSHRCYP3A4
SCHEMBL7692759 0.78 MAOB (0.47) CYP19A1MAOBMAOATSHRAPP
SCHEMBL5597378 0.77 MAOB (0.46) CYP19A1MAOBMAOATSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10995179-B2 Polyimide resin and metal-clad laminate comprising the same ETERNAL MATERIALS CO., LTD (TW) 2021-05-04 US disclosed